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[幽门螺杆菌感染根除后内镜超声引导下胃黏膜相关淋巴组织淋巴瘤的消退]

[Regression of gastric MALT lymphoma after eradication of Helicobacter pylori infection followed by endoscopic ultrasound].

作者信息

Szántó I, Domján G, Nagy P, Gonda G, Kiss J

机构信息

Egészségtudományi Kar, Sebészeti Klinika, Semmelweis Egyetem, Budapest.

出版信息

Orv Hetil. 2000 Jun 25;141(26):1455-8.

Abstract

The authors report a case of a 42 year-old female patient, who was admitted with epigastric pain and weight loss to our department. Upper gastrointestinal endoscopy two ulcerated lesions revealed in the stomach at the corpus-antrum border. Histologically the lesion proved to be a low grade, malignant B cell MALT lymphoma. Coexistent Helicobacter pylori infection was detected with modified Giemsa staining. Endoscopic ultrasonography was performed to determine the depth of tumorous infiltration of the gastric wall: the tumor was confined to the mucosa and submucosa. No regional lymph node was observed. As a result of successful Helicobacter pylori eradication the regression of MALT lymphoma occurred. The follow-up examinations showed the regression of the tumour and the patient became asymptomatic. A control ultrasonographic examinations demonstrated the normal five layers structure of the gastric wall without any alteration. In our patient Helicobacter pylori eradication was an effective therapy for gastric MALT lymphoma as well. Our results similar as are published in the literature. Endoscopic ultrasonography is very useful in the assessment of the tumours involvement of the gastric wall. In the proper follow-up examinations of the patient endoscopy, histology and endoscopic ultrasound together are the methods to apply including Helicobacter pylori control.

摘要

作者报告了一例42岁女性患者,因上腹部疼痛和体重减轻入住我院。上消化道内镜检查发现胃体-胃窦交界处有两个溃疡病变。组织学检查证实该病变为低级别恶性B细胞黏膜相关淋巴组织(MALT)淋巴瘤。改良吉姆萨染色检测到并存幽门螺杆菌感染。进行内镜超声检查以确定胃壁肿瘤浸润深度:肿瘤局限于黏膜和黏膜下层。未观察到区域淋巴结。由于成功根除幽门螺杆菌,MALT淋巴瘤出现消退。随访检查显示肿瘤消退,患者无症状。对照超声检查显示胃壁五层结构正常,无任何改变。在我们的患者中,根除幽门螺杆菌也是治疗胃MALT淋巴瘤的有效方法。我们的结果与文献报道相似。内镜超声在评估胃壁肿瘤累及情况方面非常有用。在对患者进行适当的随访检查时,内镜检查、组织学检查和内镜超声检查以及幽门螺杆菌检测都是适用的方法。

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