佛波醇酯B的不对称合成 - 第二部分：C(1)-C(19)亚基的合成及片段组装美国国立卫生研究院（GM-33328）和美国国家科学基金会提供了资金支持。感谢美国国立卫生研究院BRS共享仪器资助计划1-S10-RR04870和美国国家科学基金会（CHE 88-14019）提供核磁共振设施。 - Suppr

Asymmetric Synthesis of Phorboxazole B-Part II: Synthesis of the C(1)-C(19) Subunit and Fragment Assembly Financial support has been provided by the National Institutes of Health (GM-33328) and the National Science Foundation. The NIH BRS Shared Instrumentation Grant Program 1-S10-RR04870 and the NSF (CHE 88-14019) are acknowledged for providing NMR facilities.

作者信息

Evans DA, Fitch DM

机构信息

Department of Chemistry & Chemical Biology Harvard University Cambridge, MA 02138 (USA).

出版信息

Angew Chem Int Ed Engl. 2000 Jul 17;39(14):2536-2540. doi: 10.1002/1521-3773(20000717)39:14<2536::aid-anie2536>3.0.co;2-u.

DOI:10.1002/1521-3773(20000717)39:14<2536::aid-anie2536>3.0.co;2-u

PMID:10941128

Abstract

摘要

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Asymmetric Synthesis of Phorboxazole B-Part II: Synthesis of the C(1)-C(19) Subunit and Fragment Assembly Financial support has been provided by the National Institutes of Health (GM-33328) and the National Science Foundation. The NIH BRS Shared Instrumentation Grant Program 1-S10-RR04870 and the NSF (CHE 88-14019) are acknowledged for providing NMR facilities.佛波醇酯B的不对称合成 - 第二部分：C(1)-C(19)亚基的合成及片段组装美国国立卫生研究院（GM-33328）和美国国家科学基金会提供了资金支持。感谢美国国立卫生研究院BRS共享仪器资助计划1-S10-RR04870和美国国家科学基金会（CHE 88-14019）提供核磁共振设施。

Angew Chem Int Ed Engl. 2000 Jul 17;39(14):2536-2540. doi: 10.1002/1521-3773(20000717)39:14<2536::aid-anie2536>3.0.co;2-u.

Asymmetric Synthesis of Phorboxazole B-Part I: Synthesis of the C(20)-C(38) and C(39)-C(46) Subunits Financial support was provided by the National Institutes of Health (GM-33328) and the National Science Foundation. An American Cancer Society Postdoctoral Fellowship to T.E.S. and an NSF Predoctoral Fellowship to V.J.C. are gratefully acknowledged. The NIH BRS Shared Instrumentation Grant Program 1-S10-RR04870 and the NSF (CHE 88-14019) are acknowledged for providing NMR facilities.佛波酯B的不对称合成——第一部分：C(20)-C(38)和C(39)-C(46)亚基的合成美国国立卫生研究院（GM-33328）和美国国家科学基金会提供了资金支持。衷心感谢美国癌症协会授予T.E.S.的博士后奖学金以及美国国家科学基金会授予V.J.C.的博士前奖学金。感谢美国国立卫生研究院BRS共享仪器资助计划1-S10-RR04870和美国国家科学基金会（CHE 88-14019）提供核磁共振设施。

Angew Chem Int Ed Engl. 2000 Jul 17;39(14):2533-2536. doi: 10.1002/1521-3773(20000717)39:14<2533::aid-anie2533>3.0.co;2-b.

A Designed beta-Hairpin Containing a Natural Hydrophobic Cluster This research was supported by the National Science Foundation (CHE-9820952). J.F.E. was supported by a fellowship from the Ministerio de Educacion y Cultura (Spain) and the Fulbright Commission. The mass spectrometer was purchased in part with a National Science Foundation grant (CHE-9520868), and the NMR spectrometers were purchased in part with a National Institute Of Health grant (1 S10 RR04981). The CD spectrometer and analytical ultracentrifuge are part of the UW Biophysics Instrumentation Facility (NSF BIR-9512577).一种含有天然疏水簇的设计型β-发夹本研究得到了美国国家科学基金会（CHE - 9820952）的支持。J.F.E. 获得了西班牙教育和文化部以及富布赖特委员会的奖学金支持。质谱仪部分由美国国家科学基金会拨款（CHE - 9520868）购置，核磁共振光谱仪部分由美国国立卫生研究院拨款（1 S10 RR04981）购置。圆二色光谱仪和分析型超速离心机是华盛顿大学（UW）生物物理仪器设施（美国国家科学基金会BIR - 9512577）的一部分。

Angew Chem Int Ed Engl. 2000 Jul 3;39(13):2330-2333. doi: 10.1002/1521-3773(20000703)39:13<2330::aid-anie2330>3.0.co;2-c.

Multicarbocycle Formation Mediated by Arenoporphyrin 1,4-Diradicals: Synthesis of Picenoporphyrins This work was supported by grant CHE-99-04076 from the U.S. National Science Foundation and grant HL-22252 from the U.S. National Institutes of Health. The Bruker SMART 1000 diffractometer was funded in part by NSF Instrumentation grant CHE-98-08259.

Angew Chem Int Ed Engl. 2001 Sep 17;40(18):3439-3441. doi: 10.1002/1521-3773(20010917)40:18<3439::aid-anie3439>3.0.co;2-z.

Asymmetric, Stereocontrolled Total Synthesis of Paraherquamide A This work was supported by the NIH (Grant CA 70375). The Japanese Society for the Promotion of Science (JSPS) is acknowledged for providing support to H.T. Mass spectra were obtained on instruments supported by the NIH Shared Instrumentation Grant (GM 49631). We also wish to thank Dr. Timothy Blizzard (Merck & Co.) for providing an authentic sample of natural paraherquamide A. We also wish to acknowledge Dr. Byung H. Lee (Pharmacia-Upjohn Co.) for providing NMR spectra and an authentic specimen of 14-oxoparaherquamide B. We also wish to thank Dr. Alfredo Vazquez for assistance with purification and characterization of synthetic paraherquamide A.对羟基赫曲霉素A的不对称、立体控制全合成本研究得到了美国国立卫生研究院（拨款号CA 70375）的支持。感谢日本学术振兴会（JSPS）对H.T.的支持。质谱是在由美国国立卫生研究院共享仪器拨款（GM 49631）支持的仪器上获得的。我们还感谢蒂莫西·布莱兹德博士（默克公司）提供天然对羟基赫曲霉素A的真品样品。我们还要感谢李炳焕博士（法玛西亚-普强公司）提供核磁共振谱以及14-氧代对羟基赫曲霉素B的真品标本。我们还要感谢阿尔弗雷多·巴斯克斯博士在合成对羟基赫曲霉素A的纯化和表征方面提供的帮助。

Angew Chem Int Ed Engl. 2000 Jul 17;39(14):2540-2544. doi: 10.1002/1521-3773(20000717)39:14<2540::aid-anie2540>3.0.co;2-r.

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Angew Chem Int Ed Engl. 2001 Apr 17;40(8):1439-1442.

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(2,6-Mes(2)H(3)C(6))(2)BiH, a Stable, Molecular Hydride of a Main Group Element of the Sixth Period, and Its Conversion to the Dibismuthene (2,6-Mes(2)H(3)C(6))BiBi(2,6-Mes(2)C(6)H(3)) This work was supported by the National Science Foundation. The Bruker SMART 1000 difractometer was funded in part by NSF Instrumentation Grant CHE-9808259. Mes=2,4,6-Me(3)C(6)H(2).（2,6-二甲基苯基）₂BiH，一种第六周期主族元素的稳定分子氢化物，及其向二铋烯（2,6-二甲基苯基）BiBi（2,6-二甲基苯基）的转化本研究得到美国国家科学基金会的支持。布鲁克SMART 1000衍射仪部分由美国国家科学基金会仪器资助项目CHE-9808259资助。Mes=2,4,6-三甲基苯基。

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Angew Chem Int Ed Engl. 2000 Dec 15;39(24):4596-4599.

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