• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Immunostimulatory DNA sequences help to eradicate intracellular pathogens.

作者信息

Wagner H, Häcker H, Lipford G B

机构信息

Institute of Medical Microbiology, Immunology and Hygiene, Technical University of Munich, Germany.

出版信息

Springer Semin Immunopathol. 2000;22(1-2):147-52. doi: 10.1007/s002810000025.

DOI:10.1007/s002810000025
PMID:10944809
Abstract
摘要

相似文献

1
Immunostimulatory DNA sequences help to eradicate intracellular pathogens.免疫刺激DNA序列有助于根除细胞内病原体。
Springer Semin Immunopathol. 2000;22(1-2):147-52. doi: 10.1007/s002810000025.
2
Signal transduction induced by immunostimulatory CpG DNA.
Springer Semin Immunopathol. 2000;22(1-2):97-105. doi: 10.1007/s002810050019.
3
Mucosal adjuvanticity of immunostimulatory DNA sequences.免疫刺激DNA序列的黏膜佐剂活性
Springer Semin Immunopathol. 2000;22(1-2):133-46. doi: 10.1007/s002810000012.
4
Activation of the innate immune system by CpG oligodeoxynucleotides: immunoprotective activity and safety.CpG寡脱氧核苷酸激活天然免疫系统：免疫保护活性与安全性
Springer Semin Immunopathol. 2000;22(1-2):173-83. doi: 10.1007/s002810050027.
5
IFN-alpha beta promote priming of antigen-specific CD8+ and CD4+ T lymphocytes by immunostimulatory DNA-based vaccines.干扰素αβ可促进基于免疫刺激DNA的疫苗引发抗原特异性CD8+和CD4+ T淋巴细胞。
J Immunol. 2002 May 15;168(10):4907-13. doi: 10.4049/jimmunol.168.10.4907.
6
Activation of cutaneous dendritic cells by CpG-containing oligodeoxynucleotides: a role for dendritic cells in the augmentation of Th1 responses by immunostimulatory DNA.含CpG的寡脱氧核苷酸对皮肤树突状细胞的激活：树突状细胞在免疫刺激DNA增强Th1反应中的作用。
J Immunol. 1998 Sep 15;161(6):3042-9.
7
Activation of skin dendritic cells by immunostimulatory DNA.免疫刺激性DNA对皮肤树突状细胞的激活作用。
Springer Semin Immunopathol. 2000;22(1-2):45-54. doi: 10.1007/s002810000027.
8
Reversal of tumor-induced dendritic cell paralysis by CpG immunostimulatory oligonucleotide and anti-interleukin 10 receptor antibody.利用CpG免疫刺激寡核苷酸和抗白细胞介素10受体抗体逆转肿瘤诱导的树突状细胞麻痹
J Exp Med. 2002 Aug 19;196(4):541-9. doi: 10.1084/jem.20020732.
9
Immunostimulatory oligodeoxynucleotide isolated from genome wide screening of Mycobacterium bovis chromosomal DNA.从牛分枝杆菌染色体DNA全基因组筛选中分离出的免疫刺激性寡脱氧核苷酸。
Mol Immunol. 2006 May;43(13):2107-18. doi: 10.1016/j.molimm.2005.12.004. Epub 2006 Jan 26.
10
Dendritic cells (DC) activated by CpG DNA ex vivo are potent inducers of host resistance to an intracellular pathogen that is independent of IL-12 derived from the immunizing DC.经体外CpG DNA激活的树突状细胞（DC）是宿主对细胞内病原体产生抵抗力的有效诱导剂，这种抵抗力独立于来自免疫DC的IL-12。
J Immunol. 2004 May 15;172(10):6281-9. doi: 10.4049/jimmunol.172.10.6281.

引用本文的文献

1
TLRs as a Promise Target Along With Immune Checkpoint Against Gastric Cancer.Toll样受体作为与免疫检查点联合对抗胃癌的潜在靶点。
Front Cell Dev Biol. 2021 Jan 5;8:611444. doi: 10.3389/fcell.2020.611444. eCollection 2020.

本文引用的文献

1
Bacterial CpG-DNA activates dendritic cells in vivo: T helper cell-independent cytotoxic T cell responses to soluble proteins.细菌CpG-DNA在体内激活树突状细胞：对可溶性蛋白的不依赖辅助性T细胞的细胞毒性T细胞应答。
Eur J Immunol. 2000 Dec;30(12):3591-7. doi: 10.1002/1521-4141(200012)30:12<3591::AID-IMMU3591>3.0.CO;2-J.
2
CpG-DNA-mediated transient lymphadenopathy is associated with a state of Th1 predisposition to antigen-driven responses.CpG 脱氧核糖核酸介导的短暂性淋巴结病与 Th1 偏向抗原驱动反应的状态相关。
J Immunol. 2000 Aug 1;165(3):1228-35. doi: 10.4049/jimmunol.165.3.1228.
3
CpG-DNA activates in vivo T cell epitope presenting dendritic cells to trigger protective antiviral cytotoxic T cell responses.
CpG脱氧核糖核酸在体内激活呈递T细胞表位的树突状细胞，以触发具有保护性的抗病毒细胞毒性T细胞反应。
J Immunol. 2000 Mar 1;164(5):2372-8. doi: 10.4049/jimmunol.164.5.2372.
4
Cell type-specific activation of mitogen-activated protein kinases by CpG-DNA controls interleukin-12 release from antigen-presenting cells.CpG-DNA介导的丝裂原活化蛋白激酶的细胞类型特异性激活可控制抗原呈递细胞释放白细胞介素-12。
EMBO J. 1999 Dec 15;18(24):6973-82. doi: 10.1093/emboj/18.24.6973.
5
Phylogenetic perspectives in innate immunity.固有免疫中的系统发育观点。
Science. 1999 May 21;284(5418):1313-8. doi: 10.1126/science.284.5418.1313.
6
CpG-containing oligonucleotides are efficient adjuvants for induction of protective antiviral immune responses with T-cell peptide vaccines.含CpG的寡核苷酸是用T细胞肽疫苗诱导保护性抗病毒免疫反应的有效佐剂。
J Virol. 1999 May;73(5):4120-6. doi: 10.1128/JVI.73.5.4120-4126.1999.
7
Endotoxin-tolerant mice have mutations in Toll-like receptor 4 (Tlr4).内毒素耐受小鼠的Toll样受体4（Tlr4）存在突变。
J Exp Med. 1999 Feb 15;189(4):615-25. doi: 10.1084/jem.189.4.615.
8
Immunostimulatory CpG-oligodeoxynucleotides cause extramedullary murine hemopoiesis.免疫刺激型CpG寡脱氧核苷酸可引起小鼠髓外造血。
J Immunol. 1999 Feb 15;162(4):2368-74.
9
Bacterial DNA containing CpG motifs stimulates lymphocyte-dependent protection of mice against lethal infection with intracellular bacteria.含有CpG基序的细菌DNA可刺激淋巴细胞介导的小鼠对细胞内细菌致死性感染的保护作用。
J Immunol. 1999 Feb 15;162(4):2291-8.
10
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene.C3H/HeJ和C57BL/10ScCr小鼠中LPS信号传导缺陷：Tlr4基因的突变
Science. 1998 Dec 11;282(5396):2085-8. doi: 10.1126/science.282.5396.2085.