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十二指肠球部的酸对犬对试餐的酸和胃蛋白酶反应的影响。

Effect of acid in the duodenal bulb on acid and pepsin responses to test meal in dogs.

作者信息

Nilsson G

出版信息

Scand J Gastroenterol. 1975;10(3):279-82.

PMID:1094532
Abstract

Dogs were provided with innervated pouches of the fundic stomach and of the duodenal bulb. Gastric secretion was stimulated by a test meal. Bulbar perfusion with 0.1 N HCl profoundly ibhibited the secretion of acid. Also pepsin output and concentration of pepsin in gastric juice were reduced by bulbar acidification. The results may mean that reduction of the intrabulbar pH also plays a role in regulation of the secretion of pepsin from the stomach.

摘要

给狗制备了带神经支配的胃底部和十二指肠球部的袋状结构。通过试餐刺激胃液分泌。用0.1N盐酸灌注十二指肠球部可显著抑制胃酸分泌。十二指肠球部酸化还可降低胃蛋白酶的分泌量以及胃液中胃蛋白酶的浓度。这些结果可能意味着十二指肠球部pH值的降低在胃蛋白酶从胃中分泌的调节中也起作用。

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