Hunt D R, Wills V L
St George Upper Gastrointestinal Unit, St George Private Medical Centre, Kogarah, New South Wales, Australia.
Aust N Z J Surg. 2000 Aug;70(8):582-6. doi: 10.1046/j.1440-1622.2000.01903.x.
Laparoscopic Heller myotomy provides similar results to open Heller myotomy for the treatment of oesophageal achalasia with the advantage of quicker recovery. The present series examines the evolution of operative technique, postoperative outcome and the effect of the 'learning curve' in a group of 70 consecutive patients.
Between 1992 and 1999, details of all patients undergoing oesophagogastric myotomy for achalasia were prospectively entered on a database. Patients were followed with a biannual postal symptom questionnaire and scores were obtained for dysphagia, heartburn, regurgitation and chest pain. Comparison between preoperative and postoperative symptom scores, and case number and operative complications was made using Fisher's exact test or Mann-Whitney U-test where appropriate.
The indication for surgery was as a primary procedure in 20 cases; after failed endoscopic treatment in 48 cases; and after a 'failed' fundoplication in two cases. Myotomy was combined with a 360 degrees fundoplication in 57 patients and with an anterior fundoplication in 13 patients. Mucosal perforation occurred intraoperatively in 11 cases. Conversion to an open procedure was required in seven patients. Seven patients required a second operation. At a mean follow up of 2.9 years, symptom scores were significantly improved from preoperative values for dysphagia, regurgitation and chest pain (P < 0.001). There was no increase in the postoperative score for heartburn. The 'learning curve' contributed significantly to the length of the procedure, and the need for reoperation.
Laparoscopic Heller myotomy is a technically challenging procedure that provides good early palliation of the symptoms associated with achalasia.
腹腔镜下贲门肌切开术治疗食管贲门失弛缓症的效果与开放性贲门肌切开术相似,且恢复更快。本系列研究观察了连续70例患者的手术技术演变、术后结局及“学习曲线”的影响。
1992年至1999年,对所有因贲门失弛缓症接受食管胃肌切开术的患者详细信息进行前瞻性记录并存入数据库。每半年通过邮寄症状问卷对患者进行随访,获取吞咽困难、烧心、反流和胸痛的评分。术前和术后症状评分、病例数及手术并发症之间的比较,在适当情况下采用Fisher精确检验或Mann-Whitney U检验。
手术适应证为20例初次手术;48例内镜治疗失败后;2例胃底折叠术“失败”后。57例患者的肌切开术联合360度胃底折叠术,13例患者联合前胃底折叠术。术中发生黏膜穿孔11例。7例患者需转为开放手术。7例患者需要二次手术。平均随访2.9年,吞咽困难、反流和胸痛的症状评分较术前显著改善(P < 0.001)。烧心的术后评分没有增加。“学习曲线”对手术时间和再次手术的需求有显著影响。
腹腔镜下贲门肌切开术是一项技术上具有挑战性的手术,能有效缓解贲门失弛缓症相关的早期症状。