Singh R F, Muskelly C C
Department of Pharmacy Practice, College of Pharmacy and Allied Health, Wayne State University, Detroit, Mich. 48201, USA.
J Am Osteopath Assoc. 2000 Jul;100(7 Suppl):S14-7.
Systemic corticosteroids are known to cause adverse effects on bone loss and, with long-term use, may result in osteoporosis. There is evidence that inhaled corticosteroids at moderate to high doses may also induce bone loss. This article discusses the effects of inhaled corticosteroids on bone formation and resorption. It also offers preventive strategies to minimize bone loss associated with long-term use of inhaled corticosteroids.
已知全身用皮质类固醇会对骨质流失产生不良影响，长期使用可能导致骨质疏松。有证据表明，中高剂量吸入性皮质类固醇也可能诱发骨质流失。本文讨论了吸入性皮质类固醇对骨形成和骨吸收的影响。它还提供了预防策略，以尽量减少与长期使用吸入性皮质类固醇相关的骨质流失。
