García M J, Alegría A, Barberá R, Farré R, Lagarda M J
Nutrition and Food Chemistry, Faculty of Pharmacy, University of Valencia, Spain.
Biol Trace Elem Res. 2000 Jan;73(1):77-83. doi: 10.1385/BTER:73:1:77.
The objective was to estimate the possible influence of season or season and sex on the selenium, glutathione peroxidase (GSH-Px), copper, zinc, and superoxide dismutase (SOD) values in plasma with a view to establishing reference values. For this purpose, 55 healthy volunteers (36 women and 19 men) were selected and their whole-blood samples were collected four times a year at the beginning of each season. In the population as a whole, no statistically significant seasonal differences were detected in copper, selenium, and GSH-Px values in plasma, whereas zinc and SOD values in plasma depended on the season. In general, the variability was higher among the women. In view of the differences detected according to sex and/or season in the parameters studied, we recommend taking samples from men and women and from different seasons to establish reference values.
