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[通过傅里叶变换红外分光光度法对摩洛哥中阿特拉斯地区成人尿路结石的分析]

[Analysis of urinary calculi in adults from the Moroccan Medium Atlas by Fourier transform infrared spectrophotometry].

作者信息

Oussama A, Kzaiber F, Mernari B, Hilmi A, Semmoud A, Daudon M

机构信息

Laboratoire de Chimie de Coordination et Analytique, Faculté des Sciences, Université Chouaib Doukkali, Eljadida, Maroc.

出版信息

Prog Urol. 2000 Jun;10(3):404-10.

Abstract

OBJECTIVE

To determine the stone composition in adult patients from the medium Atlas of Morocco.

MATERIAL AND METHODS

A series of 183 calculi from adult patients (males: 123, females: 60) collected in medium Atlas of Morocco was analysed by Fourier Transform infrared spectroscopy. The stones were surgically removed (n = 168) or spontaneously passed (n = 15).

RESULTS

Kidney stones are encountered in 70.5% of calculi. The stones were twice frequent in males than in females (M/F = 2.10). Whewellite was the main component in 51.4% of the stones and 49.7% of the stone core, weddellite in only 7.1% of stones and 6.4% of the nuclei. Uric acid was predominant in 18% of stones and also 19.7% of nuclei, and carbapatite in 12.6% of stones and nuclei. All in all, whewellite was present in 77.6% of calculi and weddellite in 25.1%, carbapatite in 68.3% and PACC in 23.5%, struvite in 15.3%, uric acid in 20.8% and ammonium hydrogen urate in 14.2% of cases. Struvite stones were more frequent in females and uric acid calculi in males, in particular in patients aged more than 60 years old.

CONCLUSION

As observed in most countries, calcium oxalate was the most frequent major component of the stones (58.5%). Uric acid stones were more frequent (18%) than reported in Western countries, thus suggesting that particular dietary habits are involved in stone formation. The relatively high occurrence of struvite stones (8%) could be a marker of an insufficient early detection and treatment of chronic urinary tract infection.

摘要

目的

确定摩洛哥中阿特拉斯地区成年患者的结石成分。

材料与方法

采用傅里叶变换红外光谱法对从摩洛哥中阿特拉斯地区收集的183例成年患者(男性123例,女性60例)的结石进行分析。结石通过手术取出(n = 168)或自行排出(n = 15)。

结果

70.5%的结石为肾结石。男性结石发生率是女性的两倍(男/女 = 2.10)。水草酸钙是51.4%的结石及49.7%的结石核心的主要成分,二水草酸钙仅存在于7.1%的结石及6.4%的结石核心中。尿酸在18%的结石及19.7%的结石核心中占主导地位,碳磷灰石在12.6%的结石及结石核心中存在。总体而言,77.6%的结石中存在水草酸钙,25.1%存在二水草酸钙,68.3%存在碳磷灰石,23.5%存在磷酸铵镁钙石,15.3%存在鸟粪石,20.8%存在尿酸,14.2%存在尿酸氢铵。鸟粪石结石在女性中更常见,尿酸结石在男性中更常见,尤其是在60岁以上的患者中。

结论

正如在大多数国家所观察到的,草酸钙是结石最常见的主要成分(58.5%)。尿酸结石比西方国家报道的更为常见(18%),这表明特定的饮食习惯与结石形成有关。磷酸铵镁钙石结石相对较高的发生率(8%)可能是慢性尿路感染早期检测和治疗不足的一个标志。

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