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Purine nucleoside phosphorylase deficiency: a molecular model for selective loss of T cell function.

作者信息

Ochs U H, Chen S H, Ochs H D, Osborne W R, Scott C R

出版信息

J Immunol. 1979 Jun;122(6):2424-9.

PMID:109531
Abstract
摘要

相似文献

1
Purine nucleoside phosphorylase deficiency: a molecular model for selective loss of T cell function.嘌呤核苷磷酸化酶缺乏症：T细胞功能选择性丧失的分子模型。
J Immunol. 1979 Jun;122(6):2424-9.
2
Phosphorylation of deoxyguanosine by B and T lymphocytes: evidence against selective trapping of deoxyguanosine by T lymphocytes in purine nucleoside phosphorylase deficiency.B淋巴细胞和T淋巴细胞对脱氧鸟苷的磷酸化作用：嘌呤核苷磷酸化酶缺乏时T淋巴细胞选择性捕获脱氧鸟苷的反证。
Clin Exp Immunol. 1980 Dec;42(3):523-9.
3
Incorporation of purine nucleosides in cultured fibroblasts from a patient with purine nucleoside phosphorylase deficiency and associated T-cell immunodeficiency.嘌呤核苷磷酸化酶缺乏及相关T细胞免疫缺陷患者培养成纤维细胞中嘌呤核苷的掺入。
J Cell Physiol. 1977 Jul;92(1):109-13. doi: 10.1002/jcp.1040920113.
4
Partial deficiency of purine nucleoside phosphorylase: studies of purine and pyrimidine metabolism.嘌呤核苷磷酸化酶部分缺乏：嘌呤和嘧啶代谢研究
J Lab Clin Med. 1978 May;91(5):736-49.
5
Partial purine nucleoside phosphorylase deficiency. Studies of lymphocyte function.部分嘌呤核苷磷酸化酶缺乏症。淋巴细胞功能研究。
J Clin Invest. 1978 Apr;61(4):1071-80. doi: 10.1172/JCI109006.
6
Purine nucleoside phosphorylase deficiency associated with selective cellular immunodeficiency.嘌呤核苷磷酸化酶缺乏与选择性细胞免疫缺陷相关。
N Engl J Med. 1977 Mar 24;296(12):651-5. doi: 10.1056/NEJM197703242961203.
7
B cell hyperactivity and abnormalities in T cell markers and immunoregulatory function in a patient with nucleoside phosphorylase deficiency.一名核苷磷酸化酶缺乏症患者的B细胞功能亢进及T细胞标志物和免疫调节功能异常
Clin Exp Immunol. 1982 Dec;50(3):610-6.
8
Adenosine deaminase (ADA) and other enzyme abnormalities in immune deficiency states.免疫缺陷状态下的腺苷脱氨酶（ADA）及其他酶异常
Birth Defects Orig Artic Ser. 1978;14(6A):73-84.
9
Purine nucleoside phosphorylase deficiency: improved metabolic and immunologic function with erythrocyte transfusions.嘌呤核苷磷酸化酶缺乏症：红细胞输注改善代谢和免疫功能
N Engl J Med. 1980 Oct 23;303(17):973-7. doi: 10.1056/NEJM198010233031705.
10
[Primary immunodeficiencies and purine metabolism].[原发性免疫缺陷与嘌呤代谢]
Rev Clin Esp. 1985 Oct;177(6):247-53.

引用本文的文献

1
Cellular and molecular aspects of immune system aging.免疫系统衰老的细胞和分子层面
Mol Cell Biochem. 1981 Jul;37(3):137-56. doi: 10.1007/BF02354883.
2
Alternative metabolic fates of thymine nucleotides in human cells.人类细胞中胸腺嘧啶核苷酸的其他代谢命运。
Biochem J. 1981 Feb 15;194(2):451-61. doi: 10.1042/bj1940451.
3
Phosphorylation of deoxyguanosine by B and T lymphocytes: evidence against selective trapping of deoxyguanosine by T lymphocytes in purine nucleoside phosphorylase deficiency.B淋巴细胞和T淋巴细胞对脱氧鸟苷的磷酸化作用：嘌呤核苷磷酸化酶缺乏时T淋巴细胞选择性捕获脱氧鸟苷的反证。
Clin Exp Immunol. 1980 Dec;42(3):523-9.
4
Purine nucleoside phosphorylase deficiency. Measurement of variant protein in four families with enzyme-deficient members by an enzyme-linked immunosorbent assay.嘌呤核苷磷酸化酶缺乏症。通过酶联免疫吸附测定法对四个有酶缺陷成员的家族中的变异蛋白进行测量。
Am J Hum Genet. 1980 Nov;32(6):927-33.
5
Purinogenic lymphocytotoxicity: clues to a wider chemotherapeutic potential for the adenosine deaminase inhibitors.嘌呤生成性淋巴细胞毒性：腺苷脱氨酶抑制剂更广泛化疗潜力的线索。
Cancer Chemother Pharmacol. 1983;10(2):73-8. doi: 10.1007/BF00446213.
6
B cells as well as T cells form deoxynucleotides from either deoxyadenosine or deoxyguanosine.B细胞和T细胞均可利用脱氧腺苷或脱氧鸟苷形成脱氧核苷酸。
Clin Exp Immunol. 1984 Apr;56(1):39-48.
7
Specific cytotoxicity of arabinosylguanine toward cultured T lymphoblasts.阿糖基鸟嘌呤对培养的T淋巴母细胞的特异性细胞毒性。
J Clin Invest. 1984 Sep;74(3):951-5. doi: 10.1172/JCI111514.
8
The metabolism of deoxyguanosine and guanosine in human B and T lymphoblasts. A role for deoxyguanosine kinase activity in the selective T-cell defect associated with purine nucleoside phosphorylase deficiency.人B淋巴细胞和T淋巴细胞中脱氧鸟苷和鸟苷的代谢。脱氧鸟苷激酶活性在与嘌呤核苷磷酸化酶缺乏相关的选择性T细胞缺陷中的作用。
Biochem J. 1983 Sep 15;214(3):711-8. doi: 10.1042/bj2140711.
9
Metabolic defects in immunodeficiency diseases.免疫缺陷疾病中的代谢缺陷
Clin Exp Immunol. 1982 Jul;49(1):1-10.
10
The effect of 2'deoxyguanosine on human lymphocyte responses. II. 2'deoxyguanosine enhances PWM-induced B cell differentiation.2'-脱氧鸟苷对人淋巴细胞反应的影响。II. 2'-脱氧鸟苷增强PWM诱导的B细胞分化。
Clin Exp Immunol. 1985 Mar;59(3):659-65.