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腹腔镜辅助与开放性回结肠切除术治疗克罗恩病的比较研究

Laparoscopic-assisted vs. open ileocolic resection for Crohn's disease. A comparative study.

作者信息

Bemelman W A, Slors J F, Dunker M S, van Hogezand R A, van Deventer S J, Ringers J, Griffioen G, Gouma D J

机构信息

Department of Surgery, Leiden University Medical Center (LUMC), Amsterdam, The Netherlands.

出版信息

Surg Endosc. 2000 Aug;14(8):721-5. doi: 10.1007/s004640000186.

Abstract

BACKGROUND

The objective of this study was to compare laparoscopic-assisted ileocolic resection for Crohn's disease of the distal ileum with open surgery in two consecutive groups of patients.

METHODS

From 1995 until 1998, 48 patients underwent open ileocolic resection at the Academic Medical Center (AMC) in Amsterdam, while 30 patients had laparoscopic-assisted ileocolic resection at the Leiden University Medical Center (LUMC). Patient characteristics, perioperative course, and recovery were compared. Differences between the groups were tested using Student's t-test for independent groups and chi-square tests when appropriate.

RESULTS

The open and the laparoscopic patient groups were comparable for age, gender, body mass index (BMI), prior abdominal surgery, and length of resected bowel. The conversion rate was 6.6%. Laparoscopic operating times (138+/-SD 36 min) were significantly longer than those observed in the open group (104+/-SD 34 min). Discharge was significantly earlier in the laparoscopic group than the open group (5.7 vs 10.2 postoperative days, p<0.007). Postoperative morbidity did not differ significantly between the patients treated traditionally (14.6%) and laparoscopically (10%).

CONCLUSION

Compared to open surgery, laparoscopic ileocolic resection for Crohn's disease is associated with similar morbidity rates, a shorter hospital stay, and improved cosmetic results, justifying the laparoscopic approach as the procedure of choice.

摘要

背景

本研究的目的是比较两组连续患者中,腹腔镜辅助下对回肠末端克罗恩病行回结肠切除术与开放手术的效果。

方法

1995年至1998年期间,48例患者在阿姆斯特丹学术医疗中心(AMC)接受了开放性回结肠切除术,而30例患者在莱顿大学医学中心(LUMC)接受了腹腔镜辅助回结肠切除术。比较了患者特征、围手术期过程和恢复情况。组间差异在适当情况下使用独立样本t检验和卡方检验进行检验。

结果

开放手术组和腹腔镜手术组在年龄、性别、体重指数(BMI)、既往腹部手术史和切除肠段长度方面具有可比性。中转开腹率为6.6%。腹腔镜手术时间(138±标准差36分钟)明显长于开放手术组(104±标准差34分钟)。腹腔镜组的出院时间明显早于开放手术组(术后5.7天对10.2天,p<0.007)。传统手术治疗组(14.6%)和腹腔镜手术治疗组(10%)的术后发病率无显著差异。

结论

与开放手术相比,腹腔镜下对克罗恩病行回结肠切除术的发病率相似,住院时间更短,美容效果更好,证明腹腔镜手术是首选术式。

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