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353例精神科住院患者的烦渴与水中毒:一项流行病学及精神病理学研究

Polydipsia and water intoxication in 353 psychiatric inpatients: an epidemiological and psychopathological study.

作者信息

Mercier-Guidez E, Loas G

机构信息

University Department of Psychiatry, Hospital Philippe Pinel, 80044 Amiens cedex 01, France.

出版信息

Eur Psychiatry. 2000 Aug;15(5):306-11. doi: 10.1016/s0924-9338(00)00399-0.

Abstract

INTRODUCTION

According to several authors, water intoxication can lead to irreversible brain damage and could be the cause of nearly a fifth of the deaths of schizophrenic patients below the age of 53 years. The aim of our study was first to determine the prevalence of polydipsia and water intoxication in a population of psychiatric inpatients of a well-defined French geographic area (the Somme), and secondly to determine the clinical and socio-demographic factors associated with this disorder.

METHOD

A cross-sectional survey was done on the 450 psychiatric beds whose catchment area had a total population of 559,429 inhabitants. Using staff reports and patients' charts, the drinking habits of 353 psychiatric inpatients hospitalised during the survey in the 450 psychiatric beds of this area were examined.

RESULTS

Thirty-eight patients (10.76%; 95% confidence interval: 7.53-13.99%) among the 353 inpatients were polydipsic. About one-third of these patients were at risk of water intoxication. Polydipsia appeared to be significantly associated with male gender, smoking, celibacy and chronicity. The polydipsic patients presented also a high prevalence of schizophrenia, mental retardation, pervasive developmental disorders and high frequency of somatic disorders.

摘要

引言

据多位作者称,水中毒可导致不可逆转的脑损伤,并且可能是53岁以下精神分裂症患者近五分之一死亡的原因。我们研究的目的首先是确定法国一个明确地理区域(索姆省)的精神科住院患者中烦渴和水中毒的患病率,其次是确定与这种疾病相关的临床和社会人口学因素。

方法

对该地区450张精神科病床进行了横断面调查,其服务区域总人口为559,429名居民。利用工作人员报告和患者病历,对该地区450张精神科病床在调查期间住院的353名精神科住院患者的饮水习惯进行了检查。

结果

353名住院患者中有38名(10.76%;95%置信区间:7.53 - 13.99%)有烦渴症状。这些患者中约三分之一有水中毒风险。烦渴似乎与男性、吸烟、独身和慢性病显著相关。有烦渴症状的患者中精神分裂症、智力迟钝、广泛性发育障碍的患病率也很高,躯体疾病的发生率也很高。

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