Zamir D, Weizman J, Zamir C, Fireman Z, Weiner P
Dept. of Medicine A, Hillel Yaffe Medical Center, Hadera.
Harefuah. 1999 Jul;137(1-2):28-30, 87, 86.
A 23-year-old woman was admitted with a history of 2 weeks of cough, fever and bilateral lung infiltrates. She had been diagnosed 2 months before as having ulcerative proctitis and was treated with mesalamine, which induced a full remission, but 3 antibiotic regimens failed to improve her lung disease. Since computerized tomography revealed bilateral peripheral lung infiltrates and her eosinophile count was elevated, the diagnosis of drug-induced eosinophilic pneumonia was suggested. Mesalamine and antibiotics were stopped and oral corticosteroids begun. She became almost asymptomatic a week after mesalamine withdrawal, and the x-ray became normal.
一名23岁女性因咳嗽、发热2周及双侧肺部浸润入院。她在2个月前被诊断为溃疡性直肠炎，接受美沙拉嗪治疗后完全缓解，但3种抗生素治疗方案均未能改善其肺部疾病。由于计算机断层扫描显示双侧外周肺部浸润且嗜酸性粒细胞计数升高，故考虑药物性嗜酸性粒细胞性肺炎的诊断。停用美沙拉嗪和抗生素，开始口服糖皮质激素。停用美沙拉嗪一周后她几乎无症状，胸部X线检查恢复正常。
