Rossel M, Ceresa S, Las Heras J, Araya M
Departamento de Pediatría, Facultad de Medicina, Universidad de Chile.
Rev Med Chil. 2000 Feb;128(2):167-75.
Eosinophilic colitis is one of the clinical manifestations of allergy to cow's milk during the first year of life. We report a series of 9 infants who, under 9 months of age and while clinically well, presented rectal bleeding of variable magnitude, with or without diarrhea, shortly after a cow's milk-based formula was initiated (n = 6); yet, 3 cases received only breast feeding. Bleeding disappeared in all patients after milk withdrawal from the diet. Challenges were planned after 12 months of treatment; three patients have not yet reached this moment, 3 had a negative challenge at 12, 18 and 28 months of age and are on a complete diet, and 3 are still on cow's milk free diet because ingestion of milk at 12, 18 and 25 months still induced rectal bleeding. This series of patients gathered in 3 years, follows the trend reported in many countries that there is a relative increase of patients diagnosed with allergy conditions early in life.
嗜酸性粒细胞性结肠炎是1岁以内对牛奶过敏的临床表现之一。我们报告了一组9例婴儿，年龄在9个月以下，临床状况良好，在开始食用以牛奶为基础的配方奶后不久（n = 6），出现了不同程度的直肠出血，伴有或不伴有腹泻；然而，3例仅接受母乳喂养。所有患者在饮食中停止摄入牛奶后出血消失。计划在治疗12个月后进行激发试验；3例患者尚未达到这个阶段，3例在12、18和28个月时激发试验为阴性，目前饮食正常，还有3例仍采用无牛奶饮食，因为在12、18和25个月时摄入牛奶仍会诱发直肠出血。这组在3年内收集的患者，遵循了许多国家报道的趋势，即早年被诊断为过敏疾病的患者相对增加。
