Cusack M, Redwood S, Coltart J
Cardiothoracic Unit, St Thomas' Hospital, London SE1 7EH, UK.
Postgrad Med J. 2000 Sep;76(899):542-6. doi: 10.1136/pmj.76.899.542.
There continue to be important developments in the understanding of the pathogenesis of coronary artery disease. Advances have also been made in both the medical and interventional management of patients with ischaemic heart disease. This review has, however, not focused on the wider developments that have occurred in the area of percutaneous intervention. The vast array of new stent designs and other interventional devices have had a considerable impact on the treatment of obstructive coronary disease. In addition it is likely that further developments will be seen in areas such as intracoronary radiotherapy to reduce restenosis after PTCA and in gene therapy to promote angiogenesis in ischaemic myocardium. Both of which will be discussed in a future review of this area.
在冠心病发病机制的理解方面不断有重要进展。在缺血性心脏病患者的药物和介入治疗管理上也取得了进步。然而，本综述未聚焦于经皮介入领域所发生的更广泛进展。大量新型支架设计及其他介入装置对阻塞性冠状动脉疾病的治疗产生了相当大的影响。此外，在冠状动脉内放射治疗以减少经皮冠状动脉腔内血管成形术（PTCA）后的再狭窄以及基因治疗以促进缺血心肌血管生成等领域可能会有进一步发展。这两方面都将在该领域未来的综述中进行讨论。
