Claeson U P, Malmfors T, Wikman G, Bruhn J G
Center of Applied Pharmacognosy, Faculty of Pharmacy, Uppsala University, BMC Box 579, SE-751 23 Uppsala, Sweden.
J Ethnopharmacol. 2000 Sep;72(1-2):1-20. doi: 10.1016/s0378-8741(00)00225-7.
Adhatoda vasica (L.) Nees is a well-known plant drug in Ayurvedic and Unani medicine. It has been used for the treatment of various diseases and disorders, particularly for the respiratory tract ailments. During the last 20 years, several scientific reports on oxytocic and abortifacient effects of vasicine and alkaloid derived from the plant have appeared. This leads to questions concerning the safety of A. vasica as a herbal medicine. In this article, the major data on traditional uses as well as ethnopharmacological and toxicological studies, both published and unpublished, are reviewed and commented upon. The data have been evaluated from the point of view of correctness, reliability, relevance and importance for the overall evaluation of the safety of A. vasica.
鸭嘴花是阿育吠陀医学和尤那尼医学中一种著名的植物药。它已被用于治疗各种疾病和紊乱，特别是呼吸道疾病。在过去20年里，出现了几篇关于该植物中所含的鸭嘴花碱及其衍生生物碱的催产和堕胎作用的科学报告。这引发了关于鸭嘴花作为草药安全性的问题。在本文中，对已发表和未发表的关于其传统用途以及民族药理学和毒理学研究的主要数据进行了综述和评论。已从正确性、可靠性、相关性和重要性的角度对这些数据进行评估，以全面评估鸭嘴花的安全性。
