Kordova N, Wilt J C, Shewchuk E, Meyer W
Can J Microbiol. 1975 Jun;21(6):759-63. doi: 10.1139/m75-113.
Large amounts of particulate antigen of Chlamydia psittaci 6BC attenuated by growth in L cells were phagocytized by peritoneal mononuclear phagocytes during the 1st h after intraperitoneal inoculation. The phagocytes subsequently destroyed the immunofluorescent (IF) properties of the chlamydial antigens. It is suggested that the early damage of phagocytes by lysosomal enzymes activation induced by chlamydiae contributed to the relatively early disappearance of IF antigens from the peritoneal fluids.
大量通过在L细胞中生长而减毒的鹦鹉热衣原体6BC颗粒抗原,在腹腔接种后的第1小时内被腹腔单核吞噬细胞吞噬。随后,吞噬细胞破坏了衣原体抗原的免疫荧光(IF)特性。有人认为,衣原体诱导的溶酶体酶激活对吞噬细胞的早期损伤,导致了IF抗原在腹腔液中相对较早地消失。