Anderson V, Catroppa C, Morse S, Haritou F, Rosenfeld J
University of Melbourne, Department of Psychology, Royal Children's Hospital, Melbourne, Vic, Australia.
Pediatr Neurosurg. 2000 Jun;32(6):282-90. doi: 10.1159/000028956.
Traumatic brain injury (TBI) may have a profound impact on a child's ongoing development. Various risk factors have been found to predict outcome, but considerable variability remains unexplained. This study used a prospective, longitudinal design to examine the relationship between recovery, injury severity, age at injury and pre-injury ability. 124 children were divided according to (1) age at injury: 'young' (3-7 years) 'old' (8-12) and (2) injury severity (mild, moderate, severe). Children were evaluated acutely (T1) and at 12 months post-injury (T2), using standardized intellectual measures (IQ). Results showed a relationship between greater injury severity and poorer IQ. Age at injury was not predictive of outcome for children with mild/moderate TBI. For severe TBI, younger age at injury led to minimal recovery in IQ, while recovery from later injury was similar to that for adults. Findings suggest that children sustaining severe TBI in early childhood may be particularly at risk for residual problems post-injury.
创伤性脑损伤（TBI）可能会对儿童的持续发育产生深远影响。已发现多种风险因素可预测预后，但仍有相当大的变异性无法解释。本研究采用前瞻性纵向设计，以检验恢复情况、损伤严重程度、受伤年龄和伤前能力之间的关系。124名儿童根据（1）受伤年龄分为：“年幼”（3至7岁）、“年长”（8至12岁），以及（2）损伤严重程度（轻度、中度、重度）。使用标准化智力测量（IQ）对儿童进行急性评估（T1）和伤后12个月评估（T2）。结果显示，损伤严重程度越高，智商越低。受伤年龄并不能预测轻度/中度TBI儿童的预后。对于重度TBI，受伤时年龄较小导致智商恢复极小，而较晚受伤后的恢复情况与成人相似。研究结果表明，幼儿期遭受重度TBI的儿童受伤后出现残留问题的风险可能特别高。
