Norrashidah A W, Azizi B H, Zulfiqar M A
Paediatric Department, Hospital Kuala Lumpur, Jalan Pahang, Kuala Lumpur.
Med J Malaysia. 1999 Jun;54(2):225-9.
Acute respiratory distress syndrome (ARDS) is the final outcome of a common pathway of a variety of unrelated but massive insults to the lung. It is commonly seen in adults but also occurs in the paediatric age group. A prospective study was carried out to determine the incidence, predisposing conditions, clinical course and outcome of children with ARDS admitted to a paediatric intensive care unit (PICU). Six patients (aged 0.8 to 11 years) who fulfilled the strict criteria for ARDS were identified prospectively during a one year study period. The incidence was 1.7% of all PICU admission. The most common underlying conditions were septicemia and pneumonia. The mortality rate was 83%. Death most often occurred during the early phase of the disease. Treatment of ARDS included elimination of the cause of ARDS, early institution of mechanical ventilation with PEEP, prompt recognition and treatment of superimposed infection and careful management of additional organ failure.
急性呼吸窘迫综合征（ARDS）是各种无关但严重的肺部损伤共同通路的最终结果。它常见于成人，但也发生在儿童年龄组。进行了一项前瞻性研究，以确定入住儿科重症监护病房（PICU）的ARDS患儿的发病率、诱发因素、临床病程和结局。在为期一年的研究期间，前瞻性地确定了6例符合ARDS严格标准的患者（年龄0.8至11岁）。发病率为所有PICU入院患者的1.7%。最常见的基础疾病是败血症和肺炎。死亡率为83%。死亡最常发生在疾病的早期阶段。ARDS的治疗包括消除ARDS的病因、早期采用呼气末正压通气进行机械通气、及时识别和治疗叠加感染以及仔细处理其他器官衰竭。
