新型隐球菌中的黑色素与毒力
Melanin and virulence in Cryptococcus neoformans.
作者信息
Casadevall A, Rosas A L, Nosanchuk J D
机构信息
Department of Microbiology, Albert Einstein College of Medicine, Bronx, New York 10461, USA.
出版信息
Curr Opin Microbiol. 2000 Aug;3(4):354-8. doi: 10.1016/s1369-5274(00)00103-x.
Abstract
Melanin synthesis has been associated with virulence for the human pathogenic fungus Cryptococcus neoformans. Recent evidence indicates that C. neoformans cells synthesize melanin during infection and that this pigment protects the fungus against immune defense mechanisms.
摘要
黑色素的合成与人类致病真菌新型隐球菌的毒力有关。最近的证据表明，新型隐球菌细胞在感染过程中合成黑色素，并且这种色素可保护真菌免受免疫防御机制的影响。
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