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分娩期间及产后新生儿发生酵母菌感染的风险(作者译)

[The risk of yeast infection, of the newborn during and after delivery (author's transl)].

作者信息

van Maillot K, Leipold W

出版信息

Geburtshilfe Frauenheilkd. 1975 May;35(5):360-5.

PMID:1097300
Abstract

The importance of yeast infections in obstetrics was investigated in 200 pregnant women and their newborns. In the maternity patients the vagina was tested shortly before the delivery and the mouth of the neonates was tested 1 day prior to the discharge from the hospital. In 22% of the pregnant women and in 8,4% of the newborns, yeast (predominantly candida albicans) was found in the culture. Infants of mothers with positive cultures for yeast showed yeast more frequently (13,2%) themselves as infants of mothers with negative cultures for yeast (7,2%). Only 1 infant had clinical trush. Only 1/7 of the women who had positive cultures for yeast at delivery also had positive cultures for yeast 5--8 weeks following delivery although they were not treated. Second to the maternal vagina, the mouth of the mothers and the nursing personnel are the most important sources for yeast infections of the newborn infant. The demand to make the birth canal free of yeast at the end of the pregnancy does not appear to be justified for all obstetric units according to the results of our investigations. The incidence of a clinical yeast infection in the mature and healthy newborn infant was between 0,5 and 0,9% during the past 2 1/2 years at the Obstetric Department of the University of Erlangen, Germany. Prophylactic medication against yeast is important for all high risk neonates such as premature infants, infants with asphyxia and infants under antibiotic treatment.

摘要

对200名孕妇及其新生儿进行了研究,以探讨酵母菌感染在产科中的重要性。在产妇临分娩前不久对其阴道进行检测,在新生儿出院前1天对其口腔进行检测。在22%的孕妇和8.4%的新生儿的培养物中发现了酵母菌(主要是白色念珠菌)。酵母菌培养呈阳性的母亲所生的婴儿,其自身酵母菌感染的发生率(13.2%)高于酵母菌培养呈阴性的母亲所生的婴儿(7.2%)。只有1名婴儿有临床鹅口疮。分娩时酵母菌培养呈阳性的女性中,只有1/7在分娩后5至8周酵母菌培养仍呈阳性,尽管她们未接受治疗。仅次于产妇的阴道,母亲的口腔和护理人员是新生儿酵母菌感染的最重要来源。根据我们的调查结果,要求在妊娠末期使产道无酵母菌感染,这对所有产科单位来说似乎并无充分依据。在德国埃尔朗根大学产科,在过去两年半的时间里,成熟健康新生儿临床酵母菌感染的发生率在0.5%至0.9%之间。对所有高危新生儿,如早产儿、窒息儿和接受抗生素治疗的婴儿,预防酵母菌感染的药物治疗很重要。

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