Alteras I, Aryeli J
Mycopathologia. 1980 Oct 31;72(2):85-7. doi: 10.1007/BF00493816.
103 pregnant women, at the onset of labor, and their newborn infants, up to the forth neonatal day, were investigated for the presence of Candida albicans in their vaginal discharge stool and oral exudate. Direct microscopic examination showed the presence of pseudomycelium and budding cells in only 7 of the respective mothers (2 in vagina, 4 in the mouth and one in the stool). Culture of the vaginal discharge yielded a significant number of C. albicans colonies in 2 women, a noticeable growth in 3 and a less significant in 9. Only 17% of the mouth specimens showed a considerable quantity of the same fungus and in 7 C. albicans was detected in significant amounts in stool specimens. In the newborns C. albicans, found only by culture, was present in a small numbers (14), starting from the first neonatal day. It was found primarily in the mouth. The data obtained showed a lower incidence, than expected, of C. albicans in the vagina of pregnant women, a few hours before delivery. This suggests transmission of the organism to the newborn earlier than generally accepted.
对103名临产孕妇及其出生后至出生后第四天的新生儿进行了调查,检测其阴道分泌物、粪便和口腔渗出物中白色念珠菌的存在情况。直接显微镜检查显示,只有7名相应母亲的样本中存在假菌丝和芽生细胞(2名母亲的阴道样本、4名母亲的口腔样本和1名母亲的粪便样本)。2名孕妇的阴道分泌物培养产生了大量白色念珠菌菌落,3名孕妇的菌落生长明显,9名孕妇的菌落生长不明显。只有17%的口腔样本显示有大量相同真菌,7名孕妇的粪便样本中检测到大量白色念珠菌。在新生儿中,白色念珠菌仅通过培养发现,从出生第一天开始就有少量存在(14例)。主要在口腔中发现。所获得的数据显示,分娩前几小时孕妇阴道中白色念珠菌的发生率低于预期。这表明该病原体向新生儿的传播比普遍认为的要早。