Davis T C
Pediatrics. 1975 Jul;56(1):41-4.
Although previous reports have implicated Shigella flexneri in resistant or chronic cases of vulvovaginitis in children, no authors have described the clinical findings of this condition. The report presents four cases of persistent vulvovaginitis in prepubertal Indian girls from different reservation communities in Arizona. S. flexneri was isolated in pure culture from the vaginal discharge of each patient. All four cases were characterized by a prolonged vaginitis with a bloody, purulent discharge which responded poorly or not at all to various topical modes of therapy for nonspecific vaginitis. Three cases cleared completely when treated with orally given ampicillin for one week. The striking similarity of these cases suggests that chronic Shigella vulvovaginitis is a recognizable clinical entity and should be considered in the differential diagnosis of persistent vaginitis in children, especially in those from communities where Shigella is endemic.
尽管先前的报告认为福氏志贺菌与儿童外阴阴道炎的耐药或慢性病例有关，但尚无作者描述过这种疾病的临床发现。该报告介绍了来自亚利桑那州不同保留地社区的4例青春期前印度女孩持续性外阴阴道炎病例。从每位患者的阴道分泌物中分离出了纯培养的福氏志贺菌。所有4例病例的特征均为阴道炎病程延长，伴有血性、脓性分泌物，对各种非特异性阴道炎局部治疗方式反应不佳或完全无反应。3例患者口服氨苄西林治疗1周后完全康复。这些病例的显著相似性表明，慢性志贺菌性外阴阴道炎是一种可识别的临床实体，在儿童持续性阴道炎的鉴别诊断中应予以考虑，尤其是在志贺菌流行社区的儿童中。
