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颅内假性淋巴瘤

Intracranial pseudolymphoma.

作者信息

Donnet A, Horschowski N, Dufour H, Figarella-Branger D, Bryon P A, Berger F, Harle J R, Grisoli F

机构信息

Neurosurgical Department, CHU Timone, Marseille, France.

出版信息

J Neurooncol. 2000 Apr;47(2):175-9. doi: 10.1023/a:1006414717891.

Abstract

Intracranial pseudolymphoma is a rare tumor of the central nervous system. A 35-year-old woman presented with a frontal subcutaneous tumor. Magnetic resonance imaging revealed a left frontal meningeal tumor involving subcutaneous tissue without bone involvement. The mass was completely removed and the histological aspect of all tumor sections was that of a lymphoid hyperplasia with polyclonal proliferation. These findings were characteristic of pseudolymphoma defined as a hyperplasia of follicular and diffuse lymphoid type with assessment of its polyclonality by immunophenotyping on frozen sections, completed by molecular biology techniques.

摘要

颅内假性淋巴瘤是一种罕见的中枢神经系统肿瘤。一名35岁女性出现额部皮下肿瘤。磁共振成像显示左额叶脑膜肿瘤累及皮下组织,未累及骨骼。肿块被完全切除,所有肿瘤切片的组织学表现为淋巴细胞增生伴多克隆增殖。这些发现是假性淋巴瘤的特征,假性淋巴瘤被定义为滤泡型和弥漫型淋巴细胞增生,通过冰冻切片免疫表型分析评估其多克隆性,并辅以分子生物学技术。

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