Donnet A, Horschowski N, Dufour H, Figarella-Branger D, Bryon P A, Berger F, Harle J R, Grisoli F
Neurosurgical Department, CHU Timone, Marseille, France.
J Neurooncol. 2000 Apr;47(2):175-9. doi: 10.1023/a:1006414717891.
Intracranial pseudolymphoma is a rare tumor of the central nervous system. A 35-year-old woman presented with a frontal subcutaneous tumor. Magnetic resonance imaging revealed a left frontal meningeal tumor involving subcutaneous tissue without bone involvement. The mass was completely removed and the histological aspect of all tumor sections was that of a lymphoid hyperplasia with polyclonal proliferation. These findings were characteristic of pseudolymphoma defined as a hyperplasia of follicular and diffuse lymphoid type with assessment of its polyclonality by immunophenotyping on frozen sections, completed by molecular biology techniques.
颅内假性淋巴瘤是一种罕见的中枢神经系统肿瘤。一名35岁女性出现额部皮下肿瘤。磁共振成像显示左额叶脑膜肿瘤累及皮下组织,未累及骨骼。肿块被完全切除,所有肿瘤切片的组织学表现为淋巴细胞增生伴多克隆增殖。这些发现是假性淋巴瘤的特征,假性淋巴瘤被定义为滤泡型和弥漫型淋巴细胞增生,通过冰冻切片免疫表型分析评估其多克隆性,并辅以分子生物学技术。