Strowd Roy E, Powers Alexander K, Beaty Michael W, Ellis Thomas L
Wake Forest School of Medicine, Department of Neurology, 1 Medical Center Boulevard, Box 2669, Winston Salem, NC 27157, USA.
Wake Forest School of Medicine, Department of Neurosurgery, Winston Salem, NC, USA.
J Clin Neurosci. 2014 May;21(5):874-6. doi: 10.1016/j.jocn.2013.06.025. Epub 2013 Sep 11.
Primary central nervous system lymphoproliferative disorders comprise a heterogenous group of intracranial disease, predominantly of the high-grade non-Hodgkin's lymphoma type. We report a 56-year-old woman who developed new-onset grand mal seizures and was found to have two small uniformly enhancing dural-based lesions, which were radiologically concerning for meningiomas. Biopsy demonstrated findings consistent with benign, reactive lymphoid tissue. The patient's seizures resolved post-operatively. To our knowledge, this is the first reported patient with intracranial pseudolymphoma presenting as grand mal seizures. This case highlights this rare differential consideration in a patient with symptomatic dural-based lesion.
原发性中枢神经系统淋巴增殖性疾病包括一组异质性的颅内疾病,主要为高级别非霍奇金淋巴瘤类型。我们报告一名56岁女性,她出现了新发的癫痫大发作,经检查发现有两个均匀强化的小硬脑膜病变,影像学上怀疑为脑膜瘤。活检结果显示符合良性反应性淋巴组织。患者术后癫痫发作得到缓解。据我们所知,这是首例报告的以癫痫大发作表现的颅内假性淋巴瘤患者。该病例突出了在有症状的硬脑膜病变患者中这种罕见的鉴别诊断情况。