β-1受体阻断和β-2受体刺激在原发性高血压中的降压作用。

Antihypertensive effect of beta-1 receptor blockade and beta-2-receptor stimulation in essential hypertension.

作者信息

Andersson O, Berglund G

出版信息

Acta Med Scand. 1975 Jun;197(6):495-6. doi: 10.1111/j.0954-6820.1975.tb04958.x.

DOI:10.1111/j.0954-6820.1975.tb04958.x

Abstract

The antihypertensive effect of practolol, a beta-1-blocker, alone and in combination with a beta-2-stimulating drug, salbutamol, has been studied in a double-blind cross-over trial on 19 patients. Practolol treatment induced a significant BP reduction, while the addition of salbutamol failed to give any further decrease.

摘要

在一项针对19名患者的双盲交叉试验中，研究了β1受体阻滞剂心得宁单独使用以及与β2激动剂沙丁胺醇联合使用时的降压效果。心得宁治疗可显著降低血压，而加用沙丁胺醇后血压并未进一步下降。