Halimi J M, Giraudeau B, Vol S, Cacès E, Nivet H, Tichet J
Centre de recherche clinique, faculté de médecine de Tours.
Arch Mal Coeur Vaiss. 2000 Aug;93(8):949-51.
Former smokers exhibit decreased cardiovascular risk as compared to smokers who continue to smoke. However, smoking discontinuation results in weight gain which may be important and influence arterial pressure. From January 1st to June 30th, 1998, 12,417 volunteers (aged 20 to 69) were examined at the "Institut régional pour la santé" (IRSA, Regional Institute for Health), a group of 9 social medical centres in Western and Central France. The subjects were screened for a routine medical and biological check-up provided by their medical insurance. All of the subjects were interviewed by a trained nurse who completed a standardised questionnaire regarding personal medical history, current treatments and lifestyle behaviours (especially alcohol and smoking habits). A physician recorded clinical parameters including age, weight, height, systolic and diastolic arterial pressure. Body mass index (BMI) was calculated. Non smokers and former smokers represented 40.0% and 23.8% of the population respectively. The prevalence of a BMI 27.0 kg/m2 or greater was higher in former smokers than non smokers and current smokers. Systolic and diastolic arterial pressure in former smokers exceeded those of current smokers and non smokers by 4.2/1.1 mmHg and 2.8/1.6 mmHg respectively. Using logistic regression analysis, the relative risk of hypertension in former smokers was 1.24 (CI 95%: 1.10-1.39, p < 0.001) and 1.13 (0.995-1.29, p = 0.055) as compared to non smokers and current smokers, after adjustment for age and alcohol intake. Differences became non significant when BMI was entered in the model. The results of the present study suggest that former smoking status is associated with a higher prevalence of overweight which may cause a higher prevalence of hypertension.
与继续吸烟的人相比,曾经吸烟者的心血管疾病风险有所降低。然而,戒烟会导致体重增加,这可能很重要,并会影响动脉血压。1998年1月1日至6月30日,12417名志愿者(年龄在20至69岁之间)在法国中西部9个社会医疗中心组成的“地区健康研究所”(IRSA)接受了检查。这些受试者接受了医疗保险提供的常规医学和生物学检查。所有受试者均由一名经过培训的护士进行访谈,该护士完成了一份关于个人病史、当前治疗和生活方式行为(尤其是饮酒和吸烟习惯)的标准化问卷。一名医生记录了包括年龄、体重、身高、收缩压和舒张压在内的临床参数。计算了体重指数(BMI)。不吸烟者和曾经吸烟者分别占总人数的40.0%和23.8%。BMI≥27.0kg/m²的患病率在曾经吸烟者中高于不吸烟者和当前吸烟者。曾经吸烟者的收缩压和舒张压分别比当前吸烟者和不吸烟者高出4.2/1.1mmHg和2.8/1.6mmHg。在对年龄和酒精摄入量进行调整后,使用逻辑回归分析,曾经吸烟者患高血压的相对风险与不吸烟者和当前吸烟者相比分别为1.24(95%CI:1.10 - 1.39,p < 0.001)和1.13(0.995 - 1.29,p = 0.055)。当将BMI纳入模型时,差异变得不显著。本研究结果表明,曾经吸烟状态与超重患病率较高有关,这可能导致高血压患病率较高。