Kobayashi Y, Amaral D G
Department of Psychiatry, Center for Neuroscience and California Regional Primate Research Center, University of California, Davis, California 95616, USA.
J Comp Neurol. 2000 Oct 23;426(3):339-65. doi: 10.1002/1096-9861(20001023)426:3<339::aid-cne1>3.0.co;2-8.
This is the first in a series of reports on the neuroanatomic organization and connectivity of the macaque monkey retrosplenial cortex, i.e., areas 29 and 30. To elucidate the topographic configuration of the retrosplenial cortex and adjacent structures, we have made three-dimensional computer reconstructions of the posterior cingulate region that includes the retrosplenial cortex. The largest portion of the posterior cingulate gyrus is located dorsal to the corpus callosum. At the caudal limit of the corpus callosum, the gyrus curves around the splenium, turns laterally and forms a region called the isthmus that links the cingulate and parahippocampal gyri. The isthmus contains the caudomedial lobule, which is a rostrally oriented bulge that is made up, in part, of portions of the retrosplenial cortex. To delineate the subdivisions of the retrosplenial and adjacent cortices, we conducted a cytoarchitectonic analysis by using cerebral hemispheres that were cut at oblique angles and stained with a variety of techniques, including immunohistochemistry for nonphosphorylated neurofilament protein. The dorsal bank of the callosal sulcus and the rostral surface of the isthmus are covered by the retrosplenial cortical areas 29l, 29m, and 30, whereas most of the medial surface of the posterior cingulate gyrus and the ventral bank of the posterior cingulate sulcus consist of areas 23i and 23e. The most caudoventral portion of the cingulate gyrus is composed of an area (area 23v) that resembles the retrosplenial and posterior cingulate cortices but has a much more prominent layer IV. On the dorsal bank of the calcarine sulcus, we also defined a transitional zone, area 30v, located between the retrosplenial cortex and the prestriate visual cortex.
这是关于猕猴压后皮质(即29区和30区)的神经解剖组织和连接性系列报告中的第一篇。为阐明压后皮质及相邻结构的地形构型,我们对包含压后皮质的后扣带回区域进行了三维计算机重建。后扣带回的最大部分位于胼胝体背侧。在胼胝体的尾侧界限处,该回围绕胼胝体压部弯曲,转向外侧并形成一个称为峡部的区域,该区域连接扣带回和海马旁回。峡部包含尾内侧小叶,它是一个向前方突出的隆起,部分由压后皮质的部分组成。为描绘压后皮质及相邻皮质的细分,我们使用以斜角切开并用包括非磷酸化神经丝蛋白免疫组织化学在内的多种技术染色的大脑半球进行了细胞构筑分析。胼胝体沟的背侧缘和峡部的嘴侧表面被压后皮质区29l、29m和30覆盖,而后扣带回的大部分内侧表面和后扣带回沟的腹侧缘由23i区和23e区组成。扣带回最尾腹侧部分由一个区域(23v区)组成,该区域类似于压后皮质和后扣带回皮质,但有更明显的IV层。在距状沟的背侧缘,我们还定义了一个位于压后皮质和纹前视觉皮质之间的过渡区,即30v区。