Lloyd G, Lund V J, Howard D, Savy L
Institute of Laryngology and Otology, University College London, UK.
J Laryngol Otol. 2000 Jul;114(7):557-62. doi: 10.1258/0022215001906174.
A combination of computed tomography (CT) and magnetic resonance imaging (MRI) is now established as the optimum assessment of sinonasal malignancy. CT and MRI are of particular value in assessing the skull base, orbit and pteryo-palatine and infratemporal fossae. Although MRI offers better differentiation of tumour from surrounding tissue and fluid, coronal CT is still required for the demonstration of bone erosion particularly in the region of the cribriform plate. Thus the extent of local tumour spread may be determined with a degree of accuracy in excess of 98 per cent. However, the final determinant of penetration of the dura and orbital periosteum requires per-operative frozen section assessment. A knowledge of the tissue characteristics and site of origin can be of value in distinguishing some of the commoner sinonasal malignancies such as squamous cell carcinoma, adenocarcinoma, adenoid cystic carcinoma, olfactory neuroblastoma and chondrosarcoma. Imaging, particularly MRI also plays an important role in the post-therapeutic follow-up of patients, indicating areas of residual or recurrent disease, defining suspicious areas for biopsy. Post-operative surveillance is best achieved with three planar T1-weighted MRI, with, and without, gadolinium and axial T2-weighted sequences. The subtraction of the T1 pre- and post gadolinium T1 sequences can be of particular value in delineating recurrence.
计算机断层扫描(CT)和磁共振成像(MRI)相结合现已成为评估鼻窦恶性肿瘤的最佳方法。CT和MRI在评估颅底、眼眶、翼腭窝和颞下窝方面具有特殊价值。尽管MRI在区分肿瘤与周围组织及液体方面表现更佳,但冠状位CT对于显示骨质侵蚀,尤其是筛板区域的骨质侵蚀,仍不可或缺。因此,局部肿瘤扩散的范围可以在超过98%的准确率下得以确定。然而,硬膜和眶骨膜是否受侵的最终判定需要术中冰冻切片评估。了解组织特征和起源部位对于鉴别一些常见的鼻窦恶性肿瘤,如鳞状细胞癌、腺癌、腺样囊性癌、嗅神经母细胞瘤和软骨肉瘤具有重要价值。影像学检查,尤其是MRI,在患者治疗后的随访中也发挥着重要作用,可显示残留或复发疾病的区域,确定可疑的活检部位。术后监测最好采用三个平面的T1加权MRI序列,包括使用和不使用钆对比剂的情况以及轴位T2加权序列。T1加权序列在注射钆对比剂前后相减,对于描绘复发情况可能具有特殊价值。