Verghese J, Kuslansky G, Katz M J, Sliwinski M, Crystal H A, Buschke H, Lipton R B
Einstein Aging Study , Albert Einstein College of Medicine, Bronx, NY 10461, USA.
Neurology. 2000 Sep 26;55(6):872-4. doi: 10.1212/wnl.55.6.872.
Estrogen replacement therapy (ERT) may help maintain normal cognitive function. Nondemented surgically menopausal women on ERT (n = 10) enrolled in a longitudinal aging study performed better than age- and education-matched control subjects (n = 25) on selected tests of verbal memory and constructional ability. These results suggest that ERT initiated soon after surgical menopause can have long-term neuroprotective effects in cognitively intact women.
雌激素替代疗法(ERT)可能有助于维持正常的认知功能。参加一项纵向衰老研究的接受ERT治疗的非痴呆手术绝经后女性(n = 10)在语言记忆和结构能力的特定测试中表现优于年龄和教育程度匹配的对照受试者(n = 25)。这些结果表明,手术绝经后不久开始的ERT对认知功能正常的女性可能具有长期神经保护作用。