Milton G W, Shaw H M, Thompson J F, McCarthy W H
Skin and Cancer Foundation, Darlinghurst, New South Wales, Australia.
Australas J Dermatol. 1997 Jun;38 Suppl 1:S44-8. doi: 10.1111/j.1440-0960.1997.tb01009.x.
The incidence and prognosis of cutaneous melanoma in children under 13 years of age has always been difficult to assess. The main reasons for this difficulty include the rarity of melanoma in children, referral biases from investigating institutions, changing conceptions in the histological diagnosis of true melanoma, and the lack of large enough study groups with sufficient follow-up to estimate 10-year survival rates. The present study documents 32 cases of childhood cutaneous melanoma drawn from the records of two large referral centres in New South Wales, Australia: the Sydney Melanoma Unit and the Newcastle Melanoma Unit in order to demonstrate some of the difficulties in the assessment of incidence and prognosis in children.
13岁以下儿童皮肤黑色素瘤的发病率和预后一直难以评估。造成这种困难的主要原因包括儿童黑色素瘤罕见、调查机构的转诊偏差、对真正黑色素瘤组织学诊断的观念变化，以及缺乏足够大且有充分随访以估计10年生存率的研究组。本研究记录了从澳大利亚新南威尔士州两个大型转诊中心（悉尼黑色素瘤中心和纽卡斯尔黑色素瘤中心）的记录中选取的32例儿童皮肤黑色素瘤病例，以说明评估儿童发病率和预后方面的一些困难。
