Ailhaud G
Laboratoire de Biologie du Développement du Tissu Adipeux, Centre de Biochimie, UNSA, Faculté des Sciences, Nice, France.
Int J Obes Relat Metab Disord. 2000 Jun;24 Suppl 2:S1-3. doi: 10.1038/sj.ijo.0801267.
The objective is to present a brief overview of peptide and non-peptide factors secreted from adipocytes and to describe some studies on the postulated role of the locally active triad angiotensinogen/angiotensinII/ prostacyclin in the development/enlargement of adipose tissue mass and increased blood pressure. In addition to the role of adipose tissue as an endocrine organ, the results emphasize the autocrine/paracrine mechanisms which are postulated to play a role in adipose tissue development and enlargement.
目的是简要概述脂肪细胞分泌的肽类和非肽类因子，并描述一些关于局部活性三联体血管紧张素原/血管紧张素II/前列环素在脂肪组织量增加和血压升高中假定作用的研究。除了脂肪组织作为内分泌器官的作用外，这些结果还强调了自分泌/旁分泌机制，这些机制被假定在脂肪组织的发育和增大中起作用。
