Prins Johannes B
Princess Alexandra Hospital, Ipswich Rd, Woolloongabba 4102, Australia.
Best Pract Res Clin Endocrinol Metab. 2002 Dec;16(4):639-51. doi: 10.1053/beem.2002.0222.
Adipose tissue is a highly active endocrine organ secreting a range of soluble products with both local and distant actions. These hormones have important roles in metabolism, reproduction, cardiovascular function and immunity. It is now evident that adipose endocrine function directly influences other organ systems, including the brain, liver and skeletal muscle. The endocrine function of adipose tissue is significantly regulated by nutritional status, and both are inextricably linked to the energy storage role of adipose tissue. This chapter highlights the endocrinology of adipose tissue by concentrating on functional aspects of the secreted products. The data of particular relevance to humans are highlighted, and areas in need of future research are suggested.
脂肪组织是一个高度活跃的内分泌器官，分泌一系列具有局部和远距离作用的可溶性产物。这些激素在代谢、生殖、心血管功能和免疫方面发挥着重要作用。现在很明显，脂肪内分泌功能直接影响其他器官系统，包括大脑、肝脏和骨骼肌。脂肪组织的内分泌功能受到营养状况的显著调节，并且两者都与脂肪组织的能量储存作用有着千丝万缕的联系。本章通过关注分泌产物的功能方面来突出脂肪组织的内分泌学。突出了与人类特别相关的数据，并提出了未来需要研究的领域。
