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大脑与疼痛的功能成像综述

A Review of Functional Imaging of the Brain and Pain.

作者信息

Pawl RP

机构信息

University of Illinois at Chicago, Center for Rehabilitation, Lake Forest Hospital, 660 Westmoreland Rd., Lake Forest, IL 60045, USA.

出版信息

Curr Rev Pain. 1999;3(4):249-255. doi: 10.1007/s11916-999-0042-9.

DOI:10.1007/s11916-999-0042-9
PMID:10998680
Abstract

Functional imaging of the brain is a current reality using positron emission tomography and functional magnetic imaging. This article reviews many of the reports that have emerged in the past several years using these techniques in the analysis of pain experience. The areas of the brain that appear to be functioning during the experience of pain are discussed, and the variances in findings between studies are described. The implications of the findings are noted. Although much has been learned through these techniques, it is clear that further research is needed before clinicians can use these diagnostic studies for therapeutic purposes.

摘要

利用正电子发射断层扫描和功能磁共振成像对大脑进行功能成像已成为现实。本文回顾了过去几年中使用这些技术分析疼痛体验的许多报告。文中讨论了在疼痛体验过程中似乎发挥作用的大脑区域,并描述了不同研究结果之间的差异。同时也指出了这些发现的意义。尽管通过这些技术已经了解到很多信息,但显然在临床医生能够将这些诊断研究用于治疗目的之前,还需要进一步的研究。

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本文引用的文献

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Thalamic stimulation and functional magnetic resonance imaging: localization of cortical and subcortical activation with implanted electrodes. Technical note.丘脑刺激与功能磁共振成像:利用植入电极定位皮质和皮质下激活。技术说明。
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Positron emission tomography during motor cortex stimulation for pain control.运动皮层刺激用于疼痛控制时的正电子发射断层扫描。
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Gender differences in pain perception and patterns of cerebral activation during noxious heat stimulation in humans.人类在有害热刺激过程中疼痛感知和大脑激活模式的性别差异。
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Cerebral responses to a continual tonic pain stimulus measured using positron emission tomography.使用正电子发射断层扫描测量大脑对持续强直性疼痛刺激的反应。
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