Moscato G, Perfetti L, Galdi E, Pozzi V, Minoia C
Fondazione S. Maugeri, Clinica del Lavoro e della Riabilitazione, IRCCS, Istituto Scientifico di Pavia, Allergy and Clinical Immunology Unit, Italy.
Allergy. 2000 Sep;55(9):873-8. doi: 10.1034/j.1398-9995.2000.00584.x.
HDM distribution varies between geographic areas and may be affected by housing characteristics. We quantified Der p 1 and Der f 1 and assessed the relationships between their levels and housing characteristics in homes of nonallergic subjects.
Der f 1 and Der p 1 were measured by ELISA in dust samples from living-room floors and mattresses of 44 homes of nonallergic subjects in Pavia. Information about household characteristics was obtained by questionnaire.
Der p 1 and Der f 1 concentrations (microg/g dust, median) were 0.34 and 7.8 on mattresses, and 0.15 and 0.83 on living-room floors. Higher Der f 1 levels on mattresses were associated with synthetic pillows (P<0.05), and (only when expressed as microg/m2) with bedding washing temperature of < or = 60 degrees C (P<0.05). Der f 1 levels were higher on the living-room floors of homes located on lower (< or =first) floors (P<0.05). Good correlations were found between Der p 1 and Der f 1 expressed as microg/g dust and microg/m2 on both mattresses and living-room floors.
In homes of nonallergic subjects in northern Italy, Der f 1 exceeded the threshold for sensitization in a high proportion of mattress samples.
屋尘螨分布因地理区域而异，可能受房屋特征影响。我们对Der p 1和Der f 1进行了定量，并评估了非过敏受试者家中它们的水平与房屋特征之间的关系。
通过酶联免疫吸附测定法（ELISA）测量了帕维亚44名非过敏受试者家中客厅地板和床垫灰尘样本中的Der f 1和Der p 1。通过问卷调查获取了有关家庭特征的信息。
床垫上Der p 1和Der f 1浓度（微克/克灰尘，中位数）分别为0.34和7.8，客厅地板上分别为0.15和0.83。床垫上较高的Der f 1水平与合成枕头相关（P<0.05），并且（仅当以微克/平方米表示时）与≤60摄氏度的床上用品洗涤温度相关（P<0.05）。位于较低楼层（≤一楼）房屋的客厅地板上Der f 1水平较高（P<0.05）。在床垫和客厅地板上，以微克/克灰尘和微克/平方米表示的Der p 1和Der f 1之间发现了良好的相关性。
在意大利北部非过敏受试者的家中，Der f 1在很大比例的床垫样本中超过了致敏阈值。
