Dauchel J, Jaeck D, Schang J C, Kachelhoffer J, Stock C, Marescaux J, Grenier J F
J Chir (Paris). 1975 Mar;109(3):387-401.
The authors compare the efficacy of two perfusates, Collins' solution and Perfudex, for conservation of kidneys for short periods by perfusion and hypothermic immersion. 22 dog kidneys, removed by lombotomy, were preserved for 24 hours with one or other of these solutions and then re-implanted into their host. Radio-isotopic renography, the uptake of Hg 197 Cl3 and a hippuran renogram, used to assess the function of the transplants, suggested the functional superiority of kidneys preserved with Collins solutions. Histological controls carried out beyond the 10 th post-operative week, confirmed these results. The correlations observed between these various findings also assessed the reliability of radio-isotope examinations in the exploration of renal function.
作者比较了两种灌注液（柯林斯溶液和普弗德克斯溶液）通过灌注和低温浸泡在短时间内保存肾脏的效果。通过腰椎切开术取出的22只犬肾，用其中一种溶液保存24小时，然后再植入宿主。放射性同位素肾造影、汞197氯3的摄取和马尿酸盐肾图用于评估移植肾的功能，结果表明用柯林斯溶液保存的肾脏功能更优。术后第10周以后进行的组织学对照证实了这些结果。这些不同发现之间的相关性也评估了放射性同位素检查在肾功能探查中的可靠性。
