Passik S D, Weinreb H J
Oncology Symptom Control Research, Community Cancer Care, Inc., Indianapolis, IN 46202, USA.
Adv Ther. 2000 Mar-Apr;17(2):70-83. doi: 10.1007/BF02854840.
Physicians involved in cancer pain management treat thousands of patients with opioids, whose effective analgesia improves overall functioning. Side effects generally are tolerable, and treatment can be maintained with stable doses for long periods. Problems with addiction are infrequent. Many physicians, however, assume that opioids should be used only for chronic malignant pain. Research and clinical experience have demonstrated that opioids can safely and effectively relieve most chronic moderate to severe nonmalignant pain. Fears of addiction, disciplinary action, and adverse effects result in ineffective pain management. With current information on the use of opioids in chronic nonmalignant pain, primary care physicians can overcome these obstacles. Guidelines must clearly define the role of the primary care physician in the proper management of pain and the integration of opioid therapy. Used appropriately, opioids may represent the only source of relief for many patients.
参与癌症疼痛管理的医生用阿片类药物治疗数千名患者,其有效的镇痛作用改善了整体功能。副作用通常是可以耐受的,并且治疗可以长期维持稳定剂量。成瘾问题并不常见。然而,许多医生认为阿片类药物仅应用于慢性恶性疼痛。研究和临床经验表明,阿片类药物可以安全有效地缓解大多数慢性中度至重度非恶性疼痛。对成瘾、纪律处分和不良反应的恐惧导致疼痛管理无效。有了目前关于阿片类药物在慢性非恶性疼痛中使用的信息,初级保健医生可以克服这些障碍。指南必须明确界定初级保健医生在疼痛正确管理和阿片类药物治疗整合中的作用。适当地使用,阿片类药物可能是许多患者唯一的缓解来源。