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F 类 R 因子 R100 和 R100-1 的四环素敏感突变体

Tetracycline-sensitive mutants of the F-like R factors R100 and R100-1.

作者信息

Foster T J

出版信息

Mol Gen Genet. 1975;137(1):85-88. doi: 10.1007/BF00332542.

DOI:10.1007/BF00332542
PMID:1101030
Abstract

The majority of tetracycline-sensitive (Tets) mutants of R100 and R100-1 are multisite (deletion) mutants. About 50% of these are also transfer-deficient, indicating that the Tetr locus is closely linked to the transfer genes. Tet(s) mutants with single-site lesions are also described.

摘要

R100和R100 - 1的大多数对四环素敏感（Tets）的突变体是多位点（缺失）突变体。其中约50%也是转移缺陷型，这表明四环素抗性基因座与转移基因紧密连锁。也描述了具有单一位点损伤的Tet(s)突变体。

相似文献

1
Tetracycline-sensitive mutants of the F-like R factors R100 and R100-1.F 类 R 因子 R100 和 R100-1 的四环素敏感突变体
Mol Gen Genet. 1975;137(1):85-88. doi: 10.1007/BF00332542.
2
R factor-mediated tetracycline resistance in Escherichia coli K12. Dominance of some tetracycline sensitive mutants and relief of dominance by deletion.大肠杆菌K12中R因子介导的四环素抗性。一些四环素敏感突变体的显性以及通过缺失解除显性。
Mol Gen Genet. 1976 Feb 2;143(3):339-44. doi: 10.1007/BF00269413.
3
Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K-12 chromosome.四环素抗性决定因子从R100 - 1转移至大肠杆菌K - 12染色体。
J Bacteriol. 1975 Dec;124(3):1153-8. doi: 10.1128/jb.124.3.1153-1158.1975.
4
Genetic analysis of deletions of R100-1 that are both transfer-deficient and tetracycline-sensitive.对R100-1缺失进行的遗传分析，这些缺失既缺乏转移能力又对四环素敏感。
J Gen Microbiol. 1976 Mar;93(1):133-40. doi: 10.1099/00221287-93-1-133.
5
Transposon 10 promoted deletions and inversions in the transfer genes of R100-1.转座子10促进了R100-1转移基因中的缺失和倒位。
Mol Gen Genet. 1979 Oct 2;176(1):113-20. doi: 10.1007/BF00334302.
6
Transfer among Erwinia spp. and other enterobacteria of antibiotic resistance carried on R factors.R 因子携带的抗生素抗性在欧文氏菌属细菌与其他肠杆菌之间的转移。
J Bacteriol. 1972 Oct;112(1):576-84. doi: 10.1128/jb.112.1.576-584.1972.
7
Plasmid co-integrates of prophage lambda and R factor R100.噬菌体λ和R因子R100的质粒共整合体。
J Bacteriol. 1976 Apr;126(1):166-76. doi: 10.1128/jb.126.1.166-176.1976.
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Genetic loci responsible for incompatibility on a co-integrate plasmid, R100-1.负责共整合质粒R100-1不相容性的基因位点。
J Bacteriol. 1975 Dec;124(3):1097-100. doi: 10.1128/jb.124.3.1097-1100.1975.
9
Relation between F, R1, R100 and R144 Escherichia coli K-12 donor strains in mating.大肠杆菌K-12供体菌株F、R1、R100和R144在接合中的关系。
Mol Gen Genet. 1977 Oct 20;155(2):185-9. doi: 10.1007/BF00393158.
10
R factor tetracycline and chloramphenicol resistance in Escherichia coli K12 cmlB mutants.大肠杆菌K12 cmlB突变体中R因子对四环素和氯霉素的抗性
J Gen Microbiol. 1975 Oct;90(2):303-10. doi: 10.1099/00221287-90-2-303.

引用本文的文献

1
Analysis of tetracycline resistance encoded by transposon Tn10: deletion mapping of tetracycline-sensitive point mutations and identification of two structural genes.转座子Tn10编码的四环素抗性分析：四环素敏感点突变的缺失定位及两个结构基因的鉴定。
J Bacteriol. 1983 Feb;153(2):921-9. doi: 10.1128/jb.153.2.921-929.1983.
2
A collection of strains containing genetically linked alternating antibiotic resistance elements for genetic mapping of Escherichia coli.一组含有用于大肠杆菌基因图谱分析的遗传连锁交替抗生素抗性元件的菌株。
Microbiol Rev. 1989 Mar;53(1):1-24. doi: 10.1128/mr.53.1.1-24.1989.
3
Translocation of the tetracycline resistance determinant from R100-1 to the Escherichia coli K-12 chromosome.

本文引用的文献

1
Recombination and complementation between R factors in Escheichia coli K 12.大肠杆菌K12中R因子间的重组与互补作用
Genet Res. 1971 Dec;18(3):287-97. doi: 10.1017/s0016672300012696.
2
Resistance of Escherichia coli to tetracyclines. Changes in permeability to tetracyclines in Escherichia coli bearing transferable resistance factors.大肠杆菌对四环素的耐药性。携带可转移耐药因子的大肠杆菌对四环素通透性的变化。
Biochem J. 1967 Oct;105(1):371-8. doi: 10.1042/bj1050371.
3
Deletion map of the chloramphenicol resistance region of R1 and R100-1.
四环素抗性决定因子从R100 - 1转移至大肠杆菌K - 12染色体。
J Bacteriol. 1975 Dec;124(3):1153-8. doi: 10.1128/jb.124.3.1153-1158.1975.
4
R factor-mediated tetracycline resistance in Escherichia coli K12. Dominance of some tetracycline sensitive mutants and relief of dominance by deletion.大肠杆菌K12中R因子介导的四环素抗性。一些四环素敏感突变体的显性以及通过缺失解除显性。
Mol Gen Genet. 1976 Feb 2;143(3):339-44. doi: 10.1007/BF00269413.
5
Genetic analysis of mutations in the transfer genes of pDU202 tra::Tn10 plasmids, caused by the excision of Tn10.由Tn10切除导致的pDU202 tra::Tn10质粒转移基因中突变的遗传分析。
Mol Gen Genet. 1977 Nov 29;157(1):109-18. doi: 10.1007/BF00268693.
6
Transposon 10 promoted deletions and inversions in the transfer genes of R100-1.转座子10促进了R100-1转移基因中的缺失和倒位。
Mol Gen Genet. 1979 Oct 2;176(1):113-20. doi: 10.1007/BF00334302.
7
A genetic approach to analysis of transposons.一种分析转座子的遗传学方法。
Proc Natl Acad Sci U S A. 1979 May;76(5):2376-80. doi: 10.1073/pnas.76.5.2376.
R1和R100 - 1的氯霉素抗性区域缺失图谱。
J Bacteriol. 1973 Nov;116(2):1062-3. doi: 10.1128/jb.116.2.1062-1063.1973.
4
Electron microscope heteroduplex studies of sequence relations among plasmids of Escherichia coli. II. Structure of drug resistance (R) factors and F factors.大肠杆菌质粒间序列关系的电子显微镜异源双链研究。II. 耐药性（R）因子和F因子的结构
J Mol Biol. 1973 Apr 5;75(2):235-55. doi: 10.1016/0022-2836(73)90018-1.