心血管疾病预防中的抗血小板药物：血栓形成性心脏病患者的卒中预防
Antiplatelet drugs in cardiovascular prevention: stroke prevention in patients with thrombogenic heart disease.
出版信息
Prescrire Int. 2000 Jun;9(47):87-8.
PMID:11010751
Abstract
(1) In patients with atrial fibrillation and a moderate embolic risk, aspirin reduces the risk of stroke and has a comparable risk-benefit ratio to oral anticoagulants. (2) Oral anticoagulants are superior to aspirin in patients with atrial fibrillation and a history of stroke. (3) In patients with a mechanical valve prosthesis and a high embolic risk, the oral anticoagulant + aspirin combination has a better risk-benefit ratio than oral anticoagulant alone.
摘要
（1）在中度栓塞风险的房颤患者中，阿司匹林可降低中风风险，其风险效益比与口服抗凝剂相当。（2）在有中风病史的房颤患者中，口服抗凝剂优于阿司匹林。（3）在有机械瓣膜假体且栓塞风险高的患者中，口服抗凝剂与阿司匹林联合使用的风险效益比优于单独使用口服抗凝剂。
相似文献
1
2
Antiplatelet drugs in cardiovascular prevention: stroke: acute phase and secondary prevention.心血管疾病预防中的抗血小板药物：中风：急性期与二级预防
Prescrire Int. 2000 Jun;9(47):85-7.
3
Risks and benefits of combining aspirin with anticoagulant therapy in patients with atrial fibrillation: an exploratory analysis of stroke prevention using an oral thrombin inhibitor in atrial fibrillation (SPORTIF) trials.心房颤动患者中阿司匹林与抗凝治疗联合应用的风险和获益：心房颤动口服凝血酶抑制剂预防卒中的探索性分析（SPORTIF）试验
Am Heart J. 2006 Nov;152(5):967-73. doi: 10.1016/j.ahj.2006.06.024.
4
Comparative effects of antiplatelet, anticoagulant, or combined therapy in patients with valvular and nonvalvular atrial fibrillation: a randomized multicenter study.抗血小板、抗凝或联合治疗对瓣膜性和非瓣膜性心房颤动患者的比较效果：一项随机多中心研究。
J Am Coll Cardiol. 2004 Oct 19;44(8):1557-66. doi: 10.1016/j.jacc.2004.05.084.
5
Atrial fibrillation and stroke risk prevention in real-life clinical practice.现实临床实践中的心房颤动与中风风险预防
Thromb Haemost. 2009 Mar;101(3):415-6.
6
Incidence of stroke in paroxysmal versus sustained atrial fibrillation in patients taking oral anticoagulation or combined antiplatelet therapy: an ACTIVE W Substudy.接受口服抗凝治疗或联合抗血小板治疗的阵发性与持续性心房颤动患者的卒中发生率：ACTIVE W子研究
J Am Coll Cardiol. 2007 Nov 27;50(22):2156-61. doi: 10.1016/j.jacc.2007.07.076. Epub 2007 Nov 13.
7
Oral anticoagulant treatment with and without aspirin.
Thromb Haemost. 1995 Jul;74(1):506-10.
8
Stroke prevention in atrial fibrillation--pharmacologic strategies.心房颤动的卒中预防——药物治疗策略
Indian Heart J. 2007 Jul-Aug;59(4):311-5.
9
Prevention of stroke in patients with atrial fibrillation.心房颤动患者的卒中预防
Med Lett Drugs Ther. 2009 Jun 1;51(1313):41.
10
Clopidogrel and aspirin versus aspirin alone for the prevention of stroke in patients with a history of atrial fibrillation: subgroup analysis of the CHARISMA randomized trial.氯吡格雷与阿司匹林联用及单用阿司匹林预防房颤病史患者卒中：CHARISMA随机试验的亚组分析
Cerebrovasc Dis. 2008;25(4):344-7. doi: 10.1159/000118380. Epub 2008 Feb 27.
Zotero 插件