肾脏与甲状旁腺激素之间的关系。

Relationship between the kidney and parathyroid hormone.

作者信息

Massry S G, Coburn J W, Friedler R M, Kurokawa K, Singer F R

出版信息

Nephron. 1975;15(3-5):197-222. doi: 10.1159/000180513.

Abstract

This report reviews the interrelationship between the activity of the parathyroid glands and renal function. Among the topics discussed are: effects of parathyroid hormone on various aspects of renal function such as: (1) glomerular filtration rate and renal blood flow; (2) renal handling of phosphorus, calcium, magnesium, sodium and potassium; (3) renal production of 1,25-dihydroxycholecalciferol; (4) renal handling of bicarbonate and acid-base metabolism, and (5) mechanism of action of parathyroid hormone on the renal cell. Further topics include: renal metabolism of parathyroid hormone; the kidney in hyperparathyroidism, and effects of renal failure on structure and function of the parathyroid glands.

摘要

本报告回顾了甲状旁腺活动与肾功能之间的相互关系。所讨论的主题包括：甲状旁腺激素对肾功能各个方面的影响，如：（1）肾小球滤过率和肾血流量；（2）肾脏对磷、钙、镁、钠和钾的处理；（3）肾脏产生1,25-二羟胆钙化醇；（4）肾脏对碳酸氢盐的处理和酸碱代谢，以及（5）甲状旁腺激素对肾细胞的作用机制。其他主题包括：甲状旁腺激素的肾脏代谢；甲状旁腺功能亢进中的肾脏，以及肾衰竭对甲状旁腺结构和功能的影响。