Ido K, Neo M, Asada Y, Kondo K, Morita T, Sakamoto T, Hayashi R, Kuriyama S
Department of Orthopaedic Surgery, Japanese Red Cross Society Wakayama Medical Center, Wakayama, Japan.
Arch Orthop Trauma Surg. 2000;120(9):518-20. doi: 10.1007/s004029900132.
There have been several attempts to reduce postoperative blood loss in patients undergoing total arthroplasty. Benoni et al. reported the usefulness of tranexamic acid in total knee arthroplasty (TKA). We investigated its effect in TKA and total hip arthroplasty (THA). Blood loss was significantly reduced in patients given tranexamic acid in both the TKA and THA groups, and no severe complications, such as venous or pulmonary thrombosis, were noted in any of the patients who received the agent. Administration of tranexamic acid seems to be useful for reducing postoperative blood loss in TKA and THA.
为减少接受全关节置换术患者的术后失血量，人们进行了多次尝试。贝诺尼等人报告了氨甲环酸在全膝关节置换术（TKA）中的有效性。我们研究了其在TKA和全髋关节置换术（THA）中的效果。TKA组和THA组中使用氨甲环酸的患者失血量显著减少，且接受该药物的患者均未出现严重并发症，如静脉或肺血栓形成。氨甲环酸的应用似乎有助于减少TKA和THA的术后失血量。
