Garway-Heath D F, Poinoosawmy D, Fitzke F W, Hitchings R A
Glaucoma Unit, Moorfields Eye Hospital, London, England UK. Department of Visual Science, Institute of Ophthalmology, London, England UK.
Ophthalmology. 2000 Oct;107(10):1809-15. doi: 10.1016/s0161-6420(00)00284-0.
To establish the anatomical relationship between visual field test points in the Humphrey 24-2 test pattern and regions of the optic nerve head (ONH) DESIGN: Cross-sectional study.
Glaucoma patients and suspects from the Normal Tension Glaucoma Clinic at Moorfields Eye Hospital.
Sixty-nine retinal nerve fiber layer (RNFL) photographs with well-defined RNFL defects and/or prominent bundles were digitized. An appropriately scaled Humphrey 24-2 visual field grid and an ONH reference circle, divided into 30 degrees sectors, were generated digitally. These were superimposed onto the RNFL images. The relationship of visual field test points to the circumference of the ONH was estimated by noting the proximity of test points to RNFL defects and/or prominent bundles. The position of the ONH in relation to the fovea was also noted.
The sector at the ONH corresponding to each visual field test point, the position of the ONH in relation to the fovea, and the effect of the latter on the former.
A median 22 (range, 4-58), of a possible 69, ONH positions were assigned to each visual field test point. The standard deviation of estimations was 7.2 degrees. The position of the ONH was 15.5 degrees (standard deviation 0.9 degrees ) nasal and 1.9 degrees (standard deviation 1.0 degrees ) above the fovea. The location of the ONH had a significant effect on the corresponding position at the ONH for 28 of 52 visual field test points.
A clinically useful map that relates visual field test points to regions of the ONH has been produced. The map will aid clinical evaluation of glaucoma patients and suspects, as well as form the basis for investigations of the relationship between retinal light sensitivity and ONH structure.
确定 Humphrey 24-2 测试模式中的视野测试点与视神经乳头（ONH）区域之间的解剖学关系。
横断面研究。
来自摩尔菲尔德眼科医院正常眼压性青光眼诊所的青光眼患者和疑似患者。
对 69 张具有明确视网膜神经纤维层（RNFL）缺损和/或明显纤维束的 RNFL 照片进行数字化处理。通过数字方式生成一个适当缩放的 Humphrey 24-2 视野网格和一个分为 30 度扇形的 ONH 参考圆。将这些叠加到 RNFL 图像上。通过记录测试点与 RNFL 缺损和/或明显纤维束的接近程度，估计视野测试点与 ONH 圆周的关系。还记录了 ONH 相对于中央凹的位置。
与每个视野测试点相对应的 ONH 扇形区域、ONH 相对于中央凹的位置以及后者对前者的影响。
在可能的 69 个 ONH 位置中，每个视野测试点平均分配到 22 个（范围为 4 - 58 个）。估计的标准差为 7.2 度。ONH 的位置在中央凹鼻侧 15.5 度（标准差 0.9 度）且上方 1.9 度（标准差 1.0 度）。在 52 个视野测试点中的 28 个点上，ONH 的位置对 ONH 处的相应位置有显著影响。
已制作出一张将视野测试点与 ONH 区域相关联的临床实用图谱。该图谱将有助于青光眼患者和疑似患者的临床评估，并为研究视网膜光敏感度与 ONH 结构之间的关系奠定基础。
