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Effects of delta-9-tetrahydrocannabinol on mouse spleens.

作者信息

Lefkowitz S S, Chiang C Y

出版信息

Res Commun Chem Pathol Pharmacol. 1975 Aug;11(4):659-62.

PMID:1101329
Abstract

A study was undertaken to ascertain the effects of delta-9-Tetrahydrocannabinol on the plaque forming cell response of mice immunized with sheep erythrocytes. It was found that a marked suppression of plaque forming cells occurred concomitant with a general loss of spleen cellularity following administration of delta-9-THC. These results suggest rather marked effects of this drug on antibody synthesis.

摘要

相似文献

1
Effects of delta-9-tetrahydrocannabinol on mouse spleens.
Res Commun Chem Pathol Pharmacol. 1975 Aug;11(4):659-62.
2
Studies on the effect of cortisol on the primary immune response to sheep erythrocytes in vivo by mouse spleen cells.关于皮质醇对小鼠脾细胞在体内对绵羊红细胞的初次免疫反应影响的研究。
Onderstepoort J Vet Res. 1974 Mar;41(1):29-37.
3
Modulation of immune reactivity by phenylimidothiazole salts in mice immunized by sheep red blood cells.苯并咪唑噻唑盐对经绵羊红细胞免疫的小鼠免疫反应性的调节作用。
J Immunol. 1974 Sep;113(3):779-90.
4
delta9-Tetrahydrocannabinol suppression of the primary immune response in rats.
J Toxicol Environ Health. 1975 Sep;1(1):119-25. doi: 10.1080/15287397509529312.
5
Immunosuppressive effects of 8,9-epoxyhexahydrocannabinol (EHHC).
J Pharmacol Exp Ther. 1977 Jun;201(3):573-9.
6
[Experimental studies on the immune mechanism under the influence of antibiotics].[抗生素影响下免疫机制的实验研究]
Allerg Immunol (Leipz). 1973;19(2-4):405-8.
7
Immunosuppression of mice by delta-9-tetrahydrocannabinol.用 Δ-9-四氢大麻酚对小鼠进行免疫抑制。
Res Commun Chem Pathol Pharmacol. 1978 Jan;19(1):101-7.
8
[Effect of rubomycin B and C on formation of hemagglutinins and on the content of antibody-forming cells in the spleen of mice, following administration of sheep erythrocytes as antigen].[以绵羊红细胞为抗原给药后,柔红霉素B和C对小鼠脾脏中血凝素形成及抗体形成细胞含量的影响]
Antibiotiki. 1968 Nov;13(11):1022-6.
9
Immunosuppressive effects of incomplete Freund's adjuvant on hemolytic antibody-forming cells in spleens of immunized mice.不完全弗氏佐剂对免疫小鼠脾脏中溶血抗体形成细胞的免疫抑制作用。
J Immunol. 1971 May;106(5):1389-95.
10
Biological expressions of lymphocyte activation. 3. Suppression of plaque-forming cell responses in vitro by supernatant fluids from concanavalin A-activated spleen cell cultures.淋巴细胞激活的生物学表现。3. 伴刀豆球蛋白A激活的脾细胞培养上清液对体外空斑形成细胞反应的抑制作用。
J Immunol. 1974 Apr;112(4):1360-8.

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Effects of cannabinoids on host resistance to Listeria monocytogenes and herpes simplex virus.大麻素对宿主抵抗单核细胞增生李斯特菌和单纯疱疹病毒的影响。
Infect Immun. 1979 Mar;23(3):670-4. doi: 10.1128/iai.23.3.670-674.1979.