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[经食管超声心动图诊断矛盾性和合并性肺血栓栓塞:一例临床病例]

[Diagnosis of paradoxal and concomitant pulmonary thromboembolism with transesophageal echocardiography: a clinical case].

作者信息

Abreu A, Branco L, Bento M J, Patrício L, Rasteiro R, Bico P, Salomão S, Antunes A M

机构信息

Serviço de Cardiologia, Hospital de Santa Marta, Lisboa.

出版信息

Rev Port Cardiol. 2000 Jul-Aug;19(7-8):823-8.

Abstract

There is some controversy regarding the indications for transesophageal echocardiography in patients with suspected systemic embolism. The present case report refers to a 65 year old male admitted to the hospital for ischemic acute cerebrovascular accident, which was confirmed by cerebral computerized tomography. A transthoracic echocardiogram was performed showing right atrial and ventricular dilatation. A transesophageal echocardiogram was also performed to exclude thromboembolism and clarify dilatation of the right cavities. Mild spontaneous echocontrast was present in the left atrium without images of thrombus; an interatrial septal aneurysm with patent foramen ovale was found with right to left flow; an image compatible with a very mobile, large, proximal thrombus in the main pulmonary artery was observed. A venous duplex scan was performed, demonstrating venous thrombosis in the right popliteal and femoral veins. Pulmonary arteriography showed a large thrombus in the right pulmonary branch extending to the median lobe and a smaller thrombus in the left pulmonary branch. Apparently, the patient had no predisposing factors for thromboembolism. Full-dose heparin was started followed by oral anticoagulation. An inferior vena cava filter was implanted. At hospital discharge the pulmonary thrombus had disappeared and the right cardiac cavities had returned to normal size. The interatrial aneurysm had disappeared and foramen ovale was no longer patent. After 36 months of clinical follow up on oral anticoagulation, the patient remains asymptomatic without neurological sequelae nor respiratory distress.

摘要

对于疑似系统性栓塞患者行经食管超声心动图检查的适应证存在一些争议。本病例报告涉及一名65岁男性,因缺血性急性脑血管意外入院,经脑部计算机断层扫描确诊。经胸超声心动图检查显示右心房和心室扩张。还进行了经食管超声心动图检查以排除血栓栓塞并明确右心腔扩张的原因。左心房存在轻度自发显影但未见血栓图像;发现房间隔瘤伴卵圆孔未闭且有右向左分流;观察到与主肺动脉内一个活动度大、体积大的近端血栓相符的图像。进行了静脉双功超声扫描,显示右腘静脉和股静脉有静脉血栓形成。肺动脉造影显示右肺分支有一个大血栓延伸至中叶,左肺分支有一个较小的血栓。显然,该患者没有血栓栓塞的易感因素。开始使用全剂量肝素,随后进行口服抗凝治疗。植入了下腔静脉滤器。出院时肺血栓消失,右心腔恢复正常大小。房间隔瘤消失,卵圆孔不再开放。在口服抗凝治疗的36个月临床随访中,患者无症状,无神经后遗症也无呼吸窘迫。

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