McGlinchey P G, McCluskey D R
Department of General Medicine, Royal Victoria Hospital, Belfast, Northern Ireland.
Am J Med Sci. 2000 Sep;320(3):212-3. doi: 10.1097/00000441-200009000-00014.
We report the first documented case in the literature of hereditary angioedema presenting after commencement of estrogen replacement therapy for menopausal symptoms. The late presentation of the disease and the precipitation of attacks by physiological doses of estrogen replacement therapy make this a highly unusual case. The pathophysiology of hereditary angioedema and its hormonal links are discussed.