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1
Kinetic studies of circulating lymphocytes in malignant lymphatic disease using the impulse cytophotometer.使用脉冲细胞光度计对恶性淋巴疾病中循环淋巴细胞进行的动力学研究。
Br J Cancer Suppl. 1975 Mar;2:156-61.
2
[Impulse cytophotometry studies of bone marrow and blood cells in children with acute lymphoblastic leukemia (ALL). 2. Lymphatic cells in blood].[急性淋巴细胞白血病（ALL）患儿骨髓和血细胞的脉冲细胞光度术研究。2. 血液中的淋巴细胞]
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Culture of lymphocytes stimulated by phytohaemagglutinin (PHA) in presence of lithium in patients with lymphoma.淋巴瘤患者中在锂存在的情况下对植物血凝素（PHA）刺激的淋巴细胞进行培养。
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[Mononuclear peripheral blood cells in patients with non-Hodgkin's lymphoma synthesizing DNA in vitro].[非霍奇金淋巴瘤患者外周血单个核细胞的体外DNA合成]
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[Personal experience on the chemotherapy of leukemias and hematosarcomas].[白血病和血液肉瘤化疗的个人经验]
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6
[Chemotherapy in non-Hodgkin lymphoma].[非霍奇金淋巴瘤的化疗]
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Blastoid lymphocyte transformation assay in malignant tumours of lymphopoietic tissue: in Hodgkin's disease, reticulosarcoma, lymphosarcoma and chronic lymphatic leukaemia. Relationship to the clinical status and to the delayed type of hypersensitivity.淋巴造血组织恶性肿瘤中的原始淋巴细胞转化试验：霍奇金病、网状细胞肉瘤、淋巴肉瘤及慢性淋巴细胞白血病。与临床状态及迟发型超敏反应的关系。
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[Morphofunctional characteristics of blasts in lymphoblastic leukemia and lymphoblastic lymphosarcoma].[淋巴细胞白血病和淋巴细胞性淋巴肉瘤中原始细胞的形态功能特征]
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Non-Hodgkin's lymphoma in children.儿童非霍奇金淋巴瘤
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引用本文的文献

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Spontaneous lymphocyte transformation in relation to the number of circulating lymphocytes in Hodgkin's disease.霍奇金病中自发淋巴细胞转化与循环淋巴细胞数量的关系。
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2
Early responses to chemotherapy detected by pulse cytophotometry.通过脉冲细胞光度法检测化疗的早期反应。
Br J Cancer. 1976 Aug;34(2):153-61. doi: 10.1038/bjc.1976.137.

本文引用的文献

1
Cell population kinetics in human acute leukaemia.人类急性白血病中的细胞群体动力学
Eur J Cancer (1965). 1967 Nov;3(4):301-7. doi: 10.1016/0014-2964(67)90011-4.
2
Significance of the changes in the circulating lymphoid cells in Hodgkin's disease.霍奇金病中循环淋巴细胞变化的意义。
Br Med J. 1969 May 24;2(5655):473-7. doi: 10.1136/bmj.2.5655.473.
3
The thoracic duct lymph in Hodgkin's disease. II. Quantitative analysis of the cellular composition of the lymph.霍奇金病中的胸导管淋巴。II. 淋巴细胞成分的定量分析。
Int J Cancer. 1971 Jul 15;8(1):113-21. doi: 10.1002/ijc.2910080115.
4
Observations on abnormal cells in the peripheral blood and spleen in Hodgkin's disease.霍奇金病外周血及脾脏中异常细胞的观察
Br Med J. 1972 Jun 10;2(5814):609-11. doi: 10.1136/bmj.2.5814.609.
5
[DNA-synthesis in blood lymphocytes in malignant lymphogranuloma].[恶性淋巴肉芽肿中血淋巴细胞的DNA合成]
Acta Haematol. 1970;44(4):222-32. doi: 10.1159/000208683.
6
The selective elimination of immunologically competent cells from bone marrow and lymphatic cell mixtures. II. Mouse spleen cell fractionation on a discontinuous albumin gradient.
Transplantation. 1968 Jul;6(4):562-70. doi: 10.1097/00007890-196807000-00009.
7
Separation of viable from nonviable tumor cells by flotation on a Ficoll-Triosil mixture.
Transplantation. 1973 Apr;15(4):409-10. doi: 10.1097/00007890-197304000-00011.
8
Impaired lymphocyte transformation in Hodgkin's disease. Evidence for depletion of circulating t-lymphocytes.霍奇金病中淋巴细胞转化受损。循环T淋巴细胞耗竭的证据。
J Clin Invest. 1973 Aug;52(8):1908-17. doi: 10.1172/JCI107374.
9
The role of immunoblasts in host resistance and immunotherapy of primary sarcomata.免疫母细胞在原发性肉瘤宿主抵抗力及免疫治疗中的作用。
Adv Cancer Res. 1970;13:1-37. doi: 10.1016/s0065-230x(08)60162-1.

使用脉冲细胞光度计对恶性淋巴疾病中循环淋巴细胞进行的动力学研究。

Kinetic studies of circulating lymphocytes in malignant lymphatic disease using the impulse cytophotometer.

作者信息

Cleton F J, Smets L A, Van Rooy H, Boogaards A M

出版信息

Br J Cancer Suppl. 1975 Mar;2:156-61.

PMID:1101916
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC2149600/
Abstract

Measurements of the DNA content of mononuclear cells in the blood of patients with malignant lymphatic disease were made. In one case of acute lymphoblastic leukaemia, a large fraction of large type of blasts were in S phase. In the blood of a patient with leukaemic transformation of lymphosarcoma, a population of aneuploid tumour cells with a high percentage of cells in S phase was recognized. The increase of DNA synthesizing cells in the blood of patients with malignant lymphoma was associated with activity of the disease. The fraction of DNA synthesizing cells was raised sharply during chemotherapy.

摘要

对恶性淋巴疾病患者血液中的单核细胞进行了DNA含量测定。在一例急性淋巴细胞白血病中，大部分大型原始细胞处于S期。在一例淋巴肉瘤白血病转化患者的血液中，识别出一群非整倍体肿瘤细胞，其中处于S期的细胞百分比很高。恶性淋巴瘤患者血液中DNA合成细胞的增加与疾病活动相关。在化疗期间，DNA合成细胞的比例急剧上升。