使用脉冲细胞光度计对恶性淋巴疾病中循环淋巴细胞进行的动力学研究。
Kinetic studies of circulating lymphocytes in malignant lymphatic disease using the impulse cytophotometer.
作者信息
Cleton F J, Smets L A, Van Rooy H, Boogaards A M
出版信息
Br J Cancer Suppl. 1975 Mar;2:156-61.
Abstract
Measurements of the DNA content of mononuclear cells in the blood of patients with malignant lymphatic disease were made. In one case of acute lymphoblastic leukaemia, a large fraction of large type of blasts were in S phase. In the blood of a patient with leukaemic transformation of lymphosarcoma, a population of aneuploid tumour cells with a high percentage of cells in S phase was recognized. The increase of DNA synthesizing cells in the blood of patients with malignant lymphoma was associated with activity of the disease. The fraction of DNA synthesizing cells was raised sharply during chemotherapy.
摘要
对恶性淋巴疾病患者血液中的单核细胞进行了DNA含量测定。在一例急性淋巴细胞白血病中，大部分大型原始细胞处于S期。在一例淋巴肉瘤白血病转化患者的血液中，识别出一群非整倍体肿瘤细胞，其中处于S期的细胞百分比很高。恶性淋巴瘤患者血液中DNA合成细胞的增加与疾病活动相关。在化疗期间，DNA合成细胞的比例急剧上升。
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The thoracic duct lymph in Hodgkin's disease. II. Quantitative analysis of the cellular composition of the lymph.霍奇金病中的胸导管淋巴。II. 淋巴细胞成分的定量分析。
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Observations on abnormal cells in the peripheral blood and spleen in Hodgkin's disease.霍奇金病外周血及脾脏中异常细胞的观察
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Acta Haematol. 1970;44(4):222-32. doi: 10.1159/000208683.
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The selective elimination of immunologically competent cells from bone marrow and lymphatic cell mixtures. II. Mouse spleen cell fractionation on a discontinuous albumin gradient.
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