de Mulder P H, de Pauw B E, Wagener D J, Haanen C
Blut. 1981 Apr;42(4):249-52. doi: 10.1007/BF00996754.
Spontaneous lymphocyte transformation in relation to the number of circulating lymphocytes was studied in 54 patients with active Hodgkin's disease. Increased spontaneous DNA synthesis by peripheral lymphocytes was found in 83% of the cases studied. However, no difference was found in comparing a group of lymphopenic patients (less than 1,500 lymphocytes/microliter) to a group with normal lymphocyte count (greater than 1,500 lymphocytes/microliter). Implications of these findings are discussed
对54例活动性霍奇金病患者进行了与循环淋巴细胞数量相关的自发淋巴细胞转化研究。在所研究的病例中，83%发现外周淋巴细胞的自发DNA合成增加。然而，在比较一组淋巴细胞减少的患者（少于1500个淋巴细胞/微升）和一组淋巴细胞计数正常的患者（多于1500个淋巴细胞/微升）时，未发现差异。讨论了这些发现的意义。
