Obuobie K, Davies J S, Ogunko A, Scanlon M F
Department of Medicine, University of Wales College of Medicine, Cardiff, UK.
J Endocrinol Invest. 2000 Sep;23(8):542-4. doi: 10.1007/BF03343772.
Bilateral inferior petrosal sinus sampling for ACTH with corticotrophin releasing hormone stimulation has become an established test in differentiating pituitary Cushing's disease from Cushing's syndrome due to ectopic ACTH secretion. We report two patients with Cushing's disease who developed thromboembolic complications soon after inferior petrosal sinus sampling. We discuss the possible mechanisms leading to this complication in a syndrome in which thromboembolic complications are well recognized and highlight the need for consideration of prophylactic anticoagulation.
使用促肾上腺皮质激素释放激素刺激进行双侧岩下窦促肾上腺皮质激素采样，已成为区分垂体库欣病与异位促肾上腺皮质激素分泌所致库欣综合征的一项既定检查。我们报告了两名库欣病患者，他们在岩下窦采样后不久出现了血栓栓塞并发症。我们讨论了在一个血栓栓塞并发症已广为人知的综合征中导致这种并发症的可能机制，并强调了考虑预防性抗凝的必要性。
