Miller J D
Clin Neurosurg. 1975;22:76-105. doi: 10.1093/neurosurgery/22.cn_suppl_1.76.
Raised intracranial pressure is common in neurosurgical practice, but the clinical effects are variable. The factors which initiate intracranial hypertension are now fairly well established; the extent of the increase of intracranial pressure produced by any combination of these factors is a function of the volume-pressure status of the patient at that particular time and may be expressed in terms of brain clastance. The effects of raised intracranial pressure on the function of the brain are mediated through both changes in cerebral blood flow and brain shift or herniation. Understanding of these principles helps in selection of effective therapy for raised intracranial pressure. Ideal clinical management of raised intracranial pressure should be directed toward the identification of those situations in which intracranial pressure may become increased and should attempt to prevent intracranial hypertension before it actually occurs.
颅内压升高在神经外科实践中很常见，但临床效果因人而异。引发颅内高压的因素现已基本明确；这些因素的任何组合所导致的颅内压升高程度，取决于患者在特定时间的容积 - 压力状态，并且可以用脑弹性来表示。颅内压升高对脑功能的影响是通过脑血流量的变化以及脑移位或脑疝形成来介导的。理解这些原理有助于选择治疗颅内压升高的有效方法。理想的颅内压升高临床管理应旨在识别那些颅内压可能升高的情况，并应在颅内高压实际发生之前试图预防它。
