香草醛生物合成的新方法。
Novel approaches to the biosynthesis of vanillin.
作者信息
Walton N J, Narbad A, Faulds C, Williamson G
机构信息
Food Safety Science Division, Institute of Food Research, Norwich Research Park, Colney, NR4 7UA, Norwich, UK.
出版信息
Curr Opin Biotechnol. 2000 Oct;11(5):490-6. doi: 10.1016/s0958-1669(00)00125-7.
Abstract
Microorganisms able to produce vanillin in excess of 6g/l from ferulic acid have now been isolated. In Pseudomonas strains, the metabolic pathway from eugenol via ferulic acid to vanillin has been characterised at the enzymic and molecular genetic levels. Attempts to introduce vanillin production into other organisms by genetic engineering have begun.
摘要
现已分离出能够从阿魏酸中过量生产香兰素且产量超过6克/升的微生物。在假单胞菌菌株中，从丁香酚经阿魏酸到香兰素的代谢途径已在酶学和分子遗传学层面得到了表征。通过基因工程将香兰素生产引入其他生物体的尝试已经开始。
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