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天然增值化合物的生产:丁香酚生物转化途径的深入了解。

Production of natural value-added compounds: an insight into the eugenol biotransformation pathway.

机构信息

Department of Biotechnology, Birla Institute of Technology, Mesra, Ranchi 835215, India.

出版信息

J Ind Microbiol Biotechnol. 2013 Jun;40(6):545-50. doi: 10.1007/s10295-013-1255-9. Epub 2013 Mar 27.

Abstract

During the past few years, the production of natural value-added compounds from microbial sources has gained tremendous importance. Due to an increase in consumer demand for natural products, various food and pharmaceutical industries are continuously in search of novel metabolites obtained from microbial biotransformation. The exploitation of microbial biosynthetic pathways is both feasible and cost effective in the production of natural compounds. The environmentally compatible nature of these products is one major reason for their increasing demand. Novel approaches for natural product biogeneration will take advantage of the current studies on biotechnology, biochemical pathways and microbiology. The interest of the scientific community has shifted toward the use of microbial bioconversion for the production of valuable compounds from natural substrates. The present review focuses on eugenol biotransformation by microorganisms resulting in the formation of various value-added products such as ferulic acid, coniferyl alcohol, vanillin and vanillic acid.

摘要

在过去的几年中,从微生物来源生产天然增值化合物已经变得非常重要。由于消费者对天然产品的需求不断增加,各种食品和制药行业一直在不断寻找从微生物生物转化中获得的新型代谢物。利用微生物生物合成途径在天然化合物的生产中既可行又具有成本效益。这些产品对环境友好的特性是其需求不断增加的一个主要原因。新型天然产物生物生成方法将利用生物技术、生化途径和微生物学的当前研究成果。科学界的兴趣已经转向利用微生物生物转化从天然基质生产有价值的化合物。本综述重点介绍了微生物对丁香酚的生物转化,生成了各种增值产品,如阿魏酸、松柏醇、香草醛和香草酸。

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